3-bromo-1H-pyrrolo[3,2-b]pyridine

(R)-3-Pyrrolidin-2-ylmethyl-1H-pyrrolo[3, 2-b]pyridine.(Compound 88) Example 3 3-Bromo-4-Azaindole[00147] solution of 0.9707g (8.21 mmol) of 4-azaindole in 50 ml. of acetonitrile was placed in a 250 ml. three-neck round-bottom flask equipped with a magnetic stirrer, thermocouple, nitrogen bleed, and cooling ice bath. A total of 5.5187g (24.7 mmol, 3 eq.) of solid CuBrTo a stirredsolution of 1H-pyrrolo[3, 2-b]pyridine(1.0 g, 8.47 mmol) in dry DMF (10 ml) was added N-bromosuccinimide(1.51 g, 8.48 mmol) at 0 °C and the resultant mixture was stirredfor 1 h at the same temperature. The reaction mixture was dilutedwith saturated sodium bicarbonate solution (50 ml) and extracted withethyl acetate (2 x 150 ml). The combined organic layers were washedwith brine (50 ml) and dried (Na(R)-3-Pyrrolidin-2-ylmethyl-1H-pyrrolo[3, 2-b]pyridine.(Compound 88) Example 3 3-Bromo-4-Azaindole[00147] solution of 0.9707g (8.21 mmol) of 4-azaindole in 50 ml. of acetonitrile was placed in a 250 ml. three-neck round-bottom flask equipped with a magnetic stirrer, thermocouple, nitrogen bleed, and cooling ice bath. A total of 5.5187g (24.7 mmol, 3 eq.) of solid CuBrTo a stirredsolution of 1H-pyrrolo[3, 2-b]pyridine(1.0 g, 8.47 mmol) in dry DMF (10 ml) was added N-bromosuccinimide(1.51 g, 8.48 mmol) at 0 °C and the resultant mixture was stirredfor 1 h at the same temperature. The reaction mixture was dilutedwith saturated sodium bicarbonate solution (50 ml) and extracted withethyl acetate (2 x 150 ml). The combined organic layers were washedwith brine (50 ml) and dried (Na

Molecular Weight:197.03
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:195.96361
Monoisotopic Mass:195.96361
Topological Polar Surface Area:28.7
Heavy Atom Count:10
Complexity:129
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes