Cercosporin
-
Cercosporin
structure -
-
CAS No:
35082-49-6
-
Formula:
C29H26O10
-
Chemical Name:
Cercosporin
-
Synonyms:
Perylo[1,12-def]-1,3-dioxepin-5,11-dione,6,12-dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-,(13bR)-;Cercosporin;Perylo[1,12-def]-1,3-dioxepin-5,11-dione,6,12-dihydroxy-8,9-bis(2-hydroxypropyl)-7,10-dimethoxy-,stereoisomer;(13bR)-6,12-Dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxyperylo[1,12-def]-1,3-dioxepin-5,11-dione;(+)-Cercosporin;NSC 153111
-
CAS No:
Characteristics
152
1.59±0.1 g/cm3(Predicted)
241 °C
chloroform: soluble 9.80 - 10.20mg/mL, clear, red to red-brown
2-8°C
Cercosporin Use and Manufacturing
Cercosporin (CGP049090) is a perylenequinone reported in 1957 as the causative agent of soy bean purple speck disease due to the fungal pathogen, Cercsopsorium kikuchii, which is widely found in species of Cercosporium. Cercosporin phytotoxicity is light-activated and this process contributes to a wider biological profile as a photodynamic antiviral and antitumor active. Cercosporin is an antagonist of Tcf4/b-catenin signalling, inhibiting the expression of survivin and inducing apoptosis in several tumor cell lines.
Computed Properties
Molecular Weight:534.5
XLogP3:4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:534.15259702
Monoisotopic Mass:534.15259702
Topological Polar Surface Area:152
Heavy Atom Count:39
Complexity:988
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
- Hot Searches
- gonococcal
- iodic acid
- chemical suppliers
- 9 me bc
- propenoic acid
- triiodide