Carisbamate
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Carisbamate
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CAS No:
194085-75-1
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Formula:
C9H10ClNO3
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Chemical Name:
Carisbamate
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Synonyms:
1,2-Ethanediol,1-(2-chlorophenyl)-,2-carbamate,(1S)-;1,2-Ethanediol,1-(2-chlorophenyl)-,2-carbamate,(S)-;RWJ 333369;YKP 509;JNJ 10234094;Carisbamate;Comfyde;(2S)-2-(2-Chlorophenyl)-2-hydroxyethyl carbamate
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CAS No:
Description
Carisbamate is an organochlorine compound.|Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence.
Drug Information
Infantile spasms (West Syndrome), Lennox-Gastaut Syndrome, Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures, Neonatal seizures, Other paediatric epilepsy syndromes such as Dravet Syndrome, myoclonic astatic syndrome, epilepsy with continuous sharp-waves in sleep, idiopathic partial epilepsy, absence epilepsy
(S)-(1-2-chlorophenyl)-1,2-ethanediol 2-carbamate
Carisbamate Use and Manufacturing
Labelled Carisbamate; it is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
Human Drugs -> EU pediatric investigation plans
Computed Properties
Molecular Weight:215.63
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:215.0349209
Monoisotopic Mass:215.0349209
Topological Polar Surface Area:72.6
Heavy Atom Count:14
Complexity:201
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes