ENDOMORPHIN-2
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ENDOMORPHIN-2
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CAS No:
141801-26-5
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Formula:
C32H37N5O5
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Chemical Name:
ENDOMORPHIN-2
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Synonyms:
ENDOMORPHIN-2;ENDOMORPHIN-2 (HUMAN, BOVINE);H-TYR-PRO-PHE-PHE-NH2;YPFF-NH2;TYR-PRO-PHE-PHE-NH2;(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-2-phenyl-ethyl]pyrrolidine-2-carboxamide;L-Tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide;L-Phenylalaninamide,L-tyrosyl-L-prolyl-L-phenylalanyl-
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CAS No:
Description
Endomorphin 2, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
Solid
Characteristics
168
3.31360
White to off-white Solid
1.292±0.06 g/cm3(Predicted)
130-131℃
972.4±65.0 °C(Predicted)
541.9ºC
1.632
−20°C
Drug Information
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)
endomorphin 2
Computed Properties
Molecular Weight:571.7
XLogP3:2.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:571.27946930
Monoisotopic Mass:571.27946930
Topological Polar Surface Area:168
Heavy Atom Count:42
Complexity:911
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes