Sodium thiosulfate pentahydrate
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Sodium thiosulfate pentahydrate
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CAS No:
10102-17-7
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Formula:
H2O3S2.5H2O.2Na
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Chemical Name:
Sodium thiosulfate pentahydrate
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Synonyms:
Thiosulfuric acid (H2S2O3),sodium salt,hydrate (1:2:5);Thiosulfuric acid,disodium salt,pentahydrate;Thiosulfuric acid (H2S2O3),disodium salt,pentahydrate;Hypo;Sodium thiosulfate pentahydrate;Disodium thiosulfate pentahydrate;Sodium thiosulfate pentahydrate (Na2S2O3.5H2O);Sodium thiosulfate (Na2S2O3) pentahydrate;Disodium thiosulphate pentahydrate;1374442-74-6
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CAS No:
Description
translucent crystals or white powder Sodium thiosulfate occurs as odorless and colorless crystals, acrystalline powder or granules. It is efflorescent in dry air anddeliquescent in moist air.
Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate.|Sodium Thiosulfate is a water soluble salt and reducing agent that reacts with oxidizing agents. Although its exact mechanism of action is unknown, thiosulfate likely provides an exogenous source of sulfur, thereby hastening the detoxification of cyanide through the enzyme rhodanese (thiosulfate cyanide sulfurtransferase) which converts cyanide to the relatively nontoxic, excretable thiocyanate ion. In addition, this agent neutralizes the reactive alkylating species of nitrogen mustard, thereby decreasing skin toxicity related to nitrogen mustard extravasation. (NCI04)
Sodium thiosulfate pentahydrate Basic Attributes
248.18
247.96100
231-867-5
HX1032V43M
DTXSID6044197
C1230
28323000
Characteristics
109
0.18830
White tranparent Solid
1.01 g/mL at 25 °C
65 °C
100 C
H2O: 680 g/L (20 ºC)
Store at RT.
Abdominal cavity-mouse LD50: 5600 mg/kg
Combustible when exposed to water, humid air and oxidant
Safety Information
NONH for all modes of transport
1
36/37/38
24/25-37/39-36-26
WE6660000
Xi
The warehouse is ventilated at low temperature and dry; stored separately from oxidants, halogens and strong acids
Stable. Incompatible with strong acids, iodine, mercury.
Not Classified
Drug Information
Agents counteracting or neutralizing the action of POISONS. (See all compounds classified as Antidotes.)|Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)|Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy. (See all compounds classified as Antitubercular Agents.)|Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)
pentahydrate of sodium thiosulfate
Sodium thiosulfate pentahydrate Use and Manufacturing
Used as a dechlorinating agent after bleaching paper pulp and cotton fabrics, as a chelating agent and antioxidant in the food industry, as a detergent and disinfectant in the pharmaceutical industry; used as a dechlorination agent in natural gas, naphtha, syngas, hydrogen nitrogen and other gases Hydrogen chloride to protect downstream catalysts from poisoning. If the gas contains organic chlorine, it should be converted into hydrogen chloride through a cobalt-molybdenum hydrogenation catalyst before using a dechlorinating agent to absorb hydrogen chloride. Used as analytical reagent, mordant and fixer; suitable for the removal of chlorine such as hydrogen, nitrogen, syngas, carbon monoxide, carbon dioxide, naphtha, etc.
< 25,000 lb
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives|Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern
Computed Properties
Molecular Weight:248.19
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:9
Exact Mass:247.96124818
Monoisotopic Mass:247.96124818
Topological Polar Surface Area:109
Heavy Atom Count:12
Complexity:82.6
Covalently-Bonded Unit Count:8
Compound Is Canonicalized:Yes
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