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Sulfametrole

Sulfametrole structure

CAS No:
32909-92-5
Formula:
C9H10N4O3S2
Chemical Name:
Sulfametrole
Synonyms:
Benzenesulfonamide,4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)-;Sulfanilamide,N1-(4-methoxy-1,2,5-thiadiazol-3-yl)-;1,2,5-Thiadiazole,benzenesulfonamide deriv.;4-Amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide;Sulfametrole;3-Methoxy-4-(4′-aminobenzenesulfonamido)-1,2,5-thiadiazol
Categories:
Organic Chemistry > Amides

Description

Sulfametrole is a sulfonamide obtained by formal condensation of the sulfo group of 4-aminobenzenesulfonic acid with the amino group of 4-methoxy-1,2,5-thiadiazol-3-amine. It is a sulfonamide antibiotic, a member of thiadiazoles, an aromatic ether and a substituted aniline. It derives from a hydride of a 1,2,5-thiadiazole.|Sulfametrole is a sulfonamide antibiotic used typically in combination with trimethoprim.

Sulfametrole Basic Attributes

Molecular Weight：

286.33

Exact Mass：

286.33

EC Number：

251-288-1

UNII：

F5AK41IPQG

NCI Thesaurus Code：

C72852

Characteristics

PSA：

144 Å²

Density：

1.584±0.06 g/cm3

Melting Point：

149.5 °C

Boiling Point：

496.0±55.0 °C(Predicted)

PKA：

4.89±0.10

Drug Information

MeSH Entry Terms：

N-(4-methoxy-1,2,5-thiadiazol-3-yl)sulfanilamide

Computed Properties

Molecular Weight:286.3
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:286.01943254
Monoisotopic Mass:286.01943254
Topological Polar Surface Area:144
Heavy Atom Count:18
Complexity:365
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes