(-)-Silvestrol
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(-)-Silvestrol
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CAS No:
697235-38-4
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Formula:
C34H38O13
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Chemical Name:
(-)-Silvestrol
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Synonyms:
1H-Cyclopenta[b]benzofuran-2-carboxylic acid,6-[[(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-2,3,3a,8b-tetrahydro-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-,methyl ester,(1R,2R,3S,3aR,8bS)-;Silvestrol;(-)-Silvestrol
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CAS No:
Description
Silvestrol is an organic heterotricyclic compound that consists of a 2,3,3a,8b-tetrahydro-H-benzo[b]cyclopenta[d]furan framework substituted by hydroxy groups at positions C-1 and C-8b, a methoxycarbonyl group at C-2, a phenyl group at C-3, a 4-methoxyphenyl group at C-3a, a methoxy group at C-8 and a 1,4-dioxan-2-yloxy group at position C-6 which in turn is substituted by a methoxy group at position 3 and a 1,2-dihydroxyethyl group at position 6. Isolated from Aglaia silvestris, it exhibits antineoplastic activity. It has a role as a metabolite and an antineoplastic agent. It is an organic heterotricyclic compound, a member of dioxanes, an ether and a methyl ester.
Computed Properties
Molecular Weight:654.7
XLogP3:1.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:11
Exact Mass:654.23124126
Monoisotopic Mass:654.23124126
Topological Polar Surface Area:172
Heavy Atom Count:47
Complexity:1050
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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