SENKTIDE
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SENKTIDE
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CAS No:
106128-89-6
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Formula:
C40H55N7O11S
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Chemical Name:
SENKTIDE
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Synonyms:
succinyl(asp6;Substance P, fragment 6-11, succinyl[Asp6, NMePhe8];M.W. 842.1 C40H55N7O11S;N-(3-Carboxy-1-oxopropyl)-L-Asp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2;N-(3-Carboxy-1-oxopropyl)-L-αAsp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2;Suc-[Asp6,MePhe8]substance P(6-11);[SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P;SUCCINYL-(ASP6,N-ME-PHE8)-SUBSTANCE P (6-11)
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CAS No:
SENKTIDE Use and Manufacturing
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 μM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals.
Computed Properties
Molecular Weight:842.0
XLogP3:1.1
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:26
Exact Mass:841.36802677
Monoisotopic Mass:841.36802677
Topological Polar Surface Area:309
Heavy Atom Count:59
Complexity:1450
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes