Onilcamotide

Onilcamotide is a cancer vaccine composed of an immunogenic peptide derived from the Ras homolog family member C (RhoC; Rho-related GTP-binding protein RhoC) that is emulsified in the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, onilcamotide may stimulate the host immune system to mount a humoral and cytotoxic T-lymphocyte (CTL) response against tumor cells expressing RhoC, which results in tumor cell lysis. RhoC, a tumor-associated antigen (TAA) that is overexpressed in a variety of tumor cell types, is associated with increased metastatic potential.

Molecular Weight:2293.7
XLogP3:-11.3
Hydrogen Bond Donor Count:41
Hydrogen Bond Acceptor Count:33
Rotatable Bond Count:85
Exact Mass:2293.3582937
Monoisotopic Mass:2292.3549388
Topological Polar Surface Area:1080
Heavy Atom Count:160
Complexity:4890
Defined Atom Stereocenter Count:20
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes