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Proquazone

Proquazone structure

Proquazone 

structure
  • CAS No:

    22760-18-5

  • Formula:

    C18H18N2O

  • Chemical Name:

    Proquazone

  • Synonyms:

    2(1H)-Quinazolinone,7-methyl-1-(1-methylethyl)-4-phenyl-;2(1H)-Quinazolinone,1-isopropyl-7-methyl-4-phenyl-;7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone;1-Isopropyl-7-methyl-4-phenylquinazolin-2(1H)-one;Proquazone;1-Isopropyl-4-phenyl-7-methyl-2(1H)-quinazolinone;SaH 43-715;RU 43-715;Biarison;Sandoz 43-715;SAN 43-715;Anthrex

Description

Proquazone is a member of pyrimidines.

Proquazone Basic Attributes

278.34800

278.35

245-203-7

42VPJ2980S

DTXSID4021210

M - Musculo-skeletal system

2933990090

Characteristics

34.89000

3.95280

1.12g/cm3

137.5 °C

446ºC

220.3ºC

1.605

5.79E-08mmHg at 25°C

Drug Information

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)|Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)

1-isopropyl-4-phenyl-7-methyl-2-(1H)-quinazoline

Proquazone Use and Manufacturing

Pharmaceuticals

Computed Properties

Molecular Weight:278.3
XLogP3:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:278.141913202
Monoisotopic Mass:278.141913202
Topological Polar Surface Area:32.7
Heavy Atom Count:21
Complexity:423
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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