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Home > Encyclopedia > 5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene structure

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene 

structure
  • CAS No:

    88149-94-4

  • Formula:

    C17H12BrFO2S2

  • Chemical Name:

    5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene

  • Synonyms:

    Thiophene,5-bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-;5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene;DuP 697

Description

DuP 697 is a member of thiophenes.

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene Basic Attributes

411.30800

411.31

MRWLZPOFPA

DTXSID50236857

2934999090

Characteristics

70.76000

6.46800

1.514g/cm3

129-131 °C

454.1ºC

228.4ºC

1.621

2-8ºC

Safety Information

R36/37/38

S26; S36

Xi

Drug Information

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)

5-bromo-2-(4-fluorophenyl)-3-(4-methysulfonylphenyl)thiophene

Computed Properties

Molecular Weight:411.3
XLogP3:5.3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:409.94461
Monoisotopic Mass:409.94461
Topological Polar Surface Area:70.8
Heavy Atom Count:23
Complexity:491
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Guide of 5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene

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