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Dilazep

Dilazep structure

Dilazep 

structure
  • CAS No:

    35898-87-4

  • Formula:

    C31H44N2O10

  • Chemical Name:

    Dilazep

  • Synonyms:

    Benzoic acid,3,4,5-trimethoxy-,1,1′-[(tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl] ester;Benzoic acid,3,4,5-trimethoxy-,(tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester;1H-1,4-Diazepine,benzoic acid deriv.;Dilazep;AS 05;AS 05 (cardioprotective)

Description

Dilazep is a member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties. It has a role as a vasodilator agent, a platelet aggregation inhibitor and a cardioprotective agent. It is a member of methoxybenzenes, a benzoate ester, a diester and a diazepane. It is a conjugate base of a dilazep(2+).|Coronary vasodilator with some antiarrhythmic activity.

Dilazep Basic Attributes

604.7 g/mol

604.69

243-548-8

F8KLC2BD5Z

DTXSID9045425

C - Cardiovascular system

Characteristics

115 Ų

Safety Information

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

Asta C 4898

Computed Properties

Molecular Weight:604.7
XLogP3:4.1
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:18
Exact Mass:604.29959560
Monoisotopic Mass:604.29959560
Topological Polar Surface Area:115
Heavy Atom Count:43
Complexity:727
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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