Pumitepa
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Pumitepa
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CAS No:
42061-52-9
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Formula:
C12H19N8OP
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Chemical Name:
Pumitepa
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Synonyms:
Phosphinic amide,P,P-bis(1-aziridinyl)-N-[2-(dimethylamino)-7-methyl-7H-purin-6-yl]-;P,P-Bis(1-aziridinyl)-N-[2-(dimethylamino)-7-methyl-7H-purin-6-yl]phosphinic amide;2-Dimethylamino-6-diethyleniminophosphamido-7-methylpurine;2-(Dimethylamino)-6-[bis(ethyleneimino)phosphoramido]-7-methylpurine;Fopurine;Phopurine;Pumitepa
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CAS No:
Description
Pumitepa is a thiotepa derivative with potential antineoplastic alkylating activity. Although the exact mechanism of action of pumitepa has yet to be fully elucidated, this agent appears to work through alkylation, thereby causing DNA damage and cell cycle arrest.
Computed Properties
Molecular Weight:322.31
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:322.14194426
Monoisotopic Mass:322.14194426
Topological Polar Surface Area:82
Heavy Atom Count:22
Complexity:466
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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