N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
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N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
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CAS No:
98626-61-0
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Formula:
C17H26N2O
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Chemical Name:
N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
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Synonyms:
2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-;2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-,(±)-;N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide;(±)-Ropivacaine;LEA 103/104;109964-69-4
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CAS No:
Description
Ropivacaine is the piperidinecarboxamide obtained by the formal condensation of N-propylpipecolic acid and 2,6-dimethylaniline.|An anilide used as a long-acting local anesthetic. It has a differential blocking effect on sensory and motor neurons.
N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide Basic Attributes
274.4 g/mol
274.40
691-258-9
DTXSID90676137
Safety Information
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)
1 Propyl 2',6' pipecoloxylidide
Computed Properties
Molecular Weight:274.4
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:274.204513457
Monoisotopic Mass:274.204513457
Topological Polar Surface Area:32.3
Heavy Atom Count:20
Complexity:308
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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