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Home > Encyclopedia > N-pyrazin-2-ylnitrous amide

N-pyrazin-2-ylnitrous amide

N-pyrazin-2-ylnitrous amide structure

N-pyrazin-2-ylnitrous amide 

structure
  • CAS No:

    103829-56-7

  • Formula:

    C4H4N4O

  • Chemical Name:

    N-pyrazin-2-ylnitrous amide

  • Synonyms:

    diazohydroxide;NSC 361456;NSC-361456;pyrazine-2-diazohydroxide;PZDH cpd;Pyrazine diazohydroxide;N-pyrazin-2-ylnitrous amide;103829-56-7;UNII-M0610GT9KV;M0610GT9KV;diazohydroxide;N-Nitrosopyrazinamine;2-Pyrazine diazohydroxide;Pyrazine-2-diazohydroxide;N-Nitrosopyrazin-2-amine;NSC361456;Pyrazinamine, N-nitroso-;NSC 361456;BRN 0774915;N-Nitrosopyrazineamine;2-Pyrazinamine, N-nitroso-;SCHEMBL671572;CHEMBL2008749;(E)-hydroxy(pyrazin-2-yl)diazene;2-[(E)-Hydroxydiazenyl]pyrazine #;ZINC16940934;AKOS006273168;NCI60_003296

N-pyrazin-2-ylnitrous amide Basic Attributes

124.10 g/mol

124.03851076 g/mol

M0610GT9KV

Characteristics

67.2 Ų

Water > 9.3 (mg/mL)|Buffer, pH 4 > 15.2 (mg/mL)|Buffer, pH 9 > 12.8 (mg/mL)|Ethanol 7.2 - 14.4 (mg/mL)|Dimethylacetamide > 17.4 (mg/mL)|DMSO > 18.7 (mg/mL)|Chloroform < 0.9 (mg/mL)|Ethyl acetate < 0.7 (mg/mL)|t-Butanol < 1.1 (mg/mL)

Safety Information

Bulk: The rate of degradation was variable, ranging from =14% at room temperature in light conditions to ~4% under dark conditions. At 50 °C under light conditions, degradation averaged ~4 %. There was no apparent degradation at 50 ° C in the dark. Solution: In reagent grade water, the t1/2 was calculated to be ~27.6 hr. In phosphate buffer at pH 7.32, tilt was found to be 91 min. In borate buffer at pH 8.98, tilt was found to be 53.8 hr.

Drug Information

diazohydroxide

Computed Properties

Molecular Weight:124.10
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:124.03851076
Monoisotopic Mass:124.03851076
Topological Polar Surface Area:67.2
Heavy Atom Count:9
Complexity:96.6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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