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Home > Encyclopedia > (-)-Inophyllum P

(-)-Inophyllum P

(-)-Inophyllum P structure

(-)-Inophyllum P 

structure
  • CAS No:

    65025-62-9

  • Formula:

    C25H24O5

  • Chemical Name:

    (-)-Inophyllum P

  • Synonyms:

    2H,6H,10H-Benzo[1,2-b:3,4-b′:5,6-b′′]tripyran-2-one,11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-,(10S,11R,12S)-;2H,6H,10H-Benzo[1,2-b:3,4-b′:5,6-b′′]tripyran-2-one,11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-,[10S-(10α,11β,12β)]-;Soulattrolide;(-)-Inophyllum P;(-)-Soulattrolide

Description

Soulattrolide is a member of the class of coumarins that is 11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one substituted by a phenyl group at position 4, methyl groups at positions 6, 6, 10 and 11 and a hydroxy group at position 12 (the 10S,11R,12S stereoisomer). Isolated from Calophyllum brasiliense and Calophyllum soulattri, it exhibits anti-HIV activity. It has a role as a metabolite and a HIV-1 reverse transcriptase inhibitor. It is a member of coumarins and a secondary alcohol.

(-)-Inophyllum P Basic Attributes

404.5 g/mol

404.46

DTXSID60215355

Characteristics

65 Ų

177-181 °C

Drug Information

11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-2,6,10-benzotripyran-2-one

Computed Properties

Molecular Weight:404.5
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:404.16237386
Monoisotopic Mass:404.16237386
Topological Polar Surface Area:65
Heavy Atom Count:30
Complexity:749
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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