Difenpiramide
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Difenpiramide
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CAS No:
51484-40-3
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Formula:
C19H16N2O
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Chemical Name:
Difenpiramide
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Synonyms:
[1,1′-Biphenyl]-4-acetamide,N-2-pyridinyl-;N-2-Pyridinyl[1,1′-biphenyl]-4-acetamide;Difenpiramide;Diphenpyramide;Z 876;Difenax;NSC 305337;2-([1,1′-Biphenyl]-4-yl)-N-(pyridin-2-yl)acetamide
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CAS No:
Description
Difenpiramide is a monocarboxylic acid amide obtained by formal condensation of the carboxy group from biphenyl-4-ylacetic acid with the amino group of 2-aminopyridine. Used for treatment of rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic. It is a monocarboxylic acid amide, a member of pyridines and a member of biphenyls. It derives from a biphenyl-4-ylacetic acid.
Difenpiramide Basic Attributes
288.3 g/mol
288.34
257-235-9
Q6U5F6E1QL
305337
DTXSID10199459
M - Musculo-skeletal system
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
alpha-pyridylbiphenylacetamide
Computed Properties
Molecular Weight:288.3
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:288.126263138
Monoisotopic Mass:288.126263138
Topological Polar Surface Area:42
Heavy Atom Count:22
Complexity:343
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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