8-Hydroxyefavirenz
-
8-Hydroxyefavirenz
structure -
-
CAS No:
205754-33-2
-
Formula:
C14H9ClF3NO3
-
Chemical Name:
8-Hydroxyefavirenz
-
Synonyms:
2H-3,1-Benzoxazin-2-one,6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-,(4S)-;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-,(4S)-;(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;8-Hydroxyefavirenz;(4S)-6-Chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
-
CAS No:
Drug Information
8-hydroxyefavirenz has known human metabolites that include (2S,3S,4S,5R)-6-[[(4S)-6-chloro-4-(2-cyclopropylethynyl)-2-oxo-4-(trifluoromethyl)-1H-3,1-benzoxazin-8-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid and 8,14-dihydroxy-efavirenz.
6-chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
Computed Properties
Molecular Weight:331.67
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:331.0223053
Monoisotopic Mass:331.0223053
Topological Polar Surface Area:58.6
Heavy Atom Count:22
Complexity:551
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Request for Quotation