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Dimethisterone

Dimethisterone structure

CAS No:
79-64-1
Formula:
C23H32O2
Chemical Name:
Dimethisterone
Synonyms:
Androst-4-en-3-one,17-hydroxy-6-methyl-17-(1-propynyl)-,(6α,17β)-;Androst-4-en-3-one,17β-hydroxy-6α-methyl-17-(1-propynyl)-;Testosterone,6α-methyl-17-(1-propynyl)-;(6α,17β)-17-Hydroxy-6-methyl-17-(1-propynyl)androst-4-en-3-one;Dimethisterone;6α,21-Dimethylethisterone;6α,21-Dimethyl-17-ethynyl-17β-hydroxyandrost-4-en-3-one;17β-Hydroxy-6α-methyl-17-(1-propynyl)androst-4-en-3-one;Secrosteron;6α-Methyl-17α-propynyltestosterone;Dimethisteron;Lutogan;P-5048;6α-Methyl-17-(1-propynyl)testosterone;Dimethiderome;28779-28-4;68378-60-9;1353032-53-7
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Dimethisterone is a 3-hydroxy steroid. It has a role as an androgen.|A synthetic progestational hormone without significant estrogenic or androgenic properties. It was formerly used as the progestational component in SEQUENTIAL ORAL CONTRACEPTIVE AGENTS .

Dimethisterone Basic Attributes

Molecular Weight：

340.5

Exact Mass：

340.50

EC Number：

201-215-4

UNII：

OIC9M646C5

DSSTox ID：

DTXSID5057834

Characteristics

PSA：

37.3

XLogP3：

4.51870

Density：

1.11g/cm3

Melting Point：

102 °C

Boiling Point：

479ºC at 760 mmHg

Flash Point：

203.5ºC

Refractive Index：

1.566

Specific rotation：

D20 +10° (c = 1 in chloroform)

Drug Information

MeSH：

Oral contraceptives which owe their effectiveness to hormonal preparations. (See all compounds classified as Contraceptives, Oral, Hormonal.)|Oral contraceptives which owe their effectiveness to synthetic preparations. (See all compounds classified as Contraceptives, Oral, Synthetic.)

MeSH Entry Terms：

Androst-4-en-3-one, 17-hydroxy-6-methyl-17-(1-propynyl)-, (6alpha,17beta)-

Computed Properties

Molecular Weight:340.5
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:340.240230259
Monoisotopic Mass:340.240230259
Topological Polar Surface Area:37.3
Heavy Atom Count:25
Complexity:706
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes