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Rubiadin 1-methyl ether

Rubiadin 1-methyl ether structure

Rubiadin 1-methyl ether 

structure
  • CAS No:

    7460-43-7

  • Formula:

    C16H12O4

  • Chemical Name:

    Rubiadin 1-methyl ether

  • Synonyms:

    9,10-Anthracenedione,3-hydroxy-1-methoxy-2-methyl-;Anthraquinone,3-hydroxy-1-methoxy-2-methyl-;3-Hydroxy-1-methoxy-2-methyl-9,10-anthracenedione;Rubiadin 1-methyl ether;NSC 59063;3-Hydroxy-1-methoxy-2-methylanthraquinone

  • Categories:

    Natural Products  >  Anthraquinone and Derivatives

Description

Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].

Rubiadin 1-methyl ether Basic Attributes

268.267

268.26

MK2IXH6AUE

59063

DTXSID80225572

2914690090

Characteristics

63.6

3.92

1.4±0.1 g/cm3

291 °C

502.2±50.0 °C at 760 mmHg

193.0±23.6 °C

1.649

Drug Information

rubiadin 1-methyl ether

Computed Properties

Molecular Weight:268.26
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:268.07355886
Monoisotopic Mass:268.07355886
Topological Polar Surface Area:63.6
Heavy Atom Count:20
Complexity:419
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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