2-Hydroxy-3,4-dimethoxybenzoic acid

To a solution of 2, 3, 4-trimethoxybenzoic acid (3-A) (1.06 g, 5 mmol) in DCM (30 mL) was added BBr3 (0.5 mL, 5.5 mmol) at -20°C, the mixture was stirred at - 20°C for 30 mins. Then NaHCO3 was added to quench the reaction. 2N HC1 (50 mL) was added and the mixture was extracted with DCM to afford 2-hydroxy-3, 4-dimethoxybenzoic acid (3-B) (705 mg, 62.2percent).[04081 To a solution of 2, 3, 4-trimethoxybenzoic acid (3-A) (1.06 g, 5 mmol) in DCM (30 mL) was added BBr3 (0.5 mL, 5.5 mmol) at -20°C, the mixture was stirred at - 20°C for 30 mins. Then NaHCO3 was added to quench the reaction. 2N HC1 (50 mL) was added and the mixture was extracted with DCM to afford 2-hydroxy-3, 4-dimethoxybenzoic acid (3-B) (705 mg, 62.2percent).

Molecular Weight:198.17
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:198.05282342
Monoisotopic Mass:198.05282342
Topological Polar Surface Area:76
Heavy Atom Count:14
Complexity:205
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes