 Home > Encyclopedia > Isophthaloyl chloride

Isophthaloyl chloride

Isophthaloyl chloride structure

CAS No:
99-63-8
Formula:
C8H4Cl2O2
Chemical Name:
Isophthaloyl chloride
Synonyms:
1,3-Benzenedicarbonyl dichloride;Isophthaloyl chloride;1,3-Benzenedicarbonyl chloride;Isophthalic acid chloride;Isophthalic acid dichloride;Isophthaloyl dichloride;Isophthalyl chloride;Isophthalyl dichloride;m-Phthalic dichloride;m-Phthaloyl chloride;Isophthalic chloride;m-Benzenedicarbonyl chloride;Isothaloyl chloride;m-Phthaloyl dichloride;1,3-Bis(chlorocarbonyl)benzene;1,3-Di(chlorocarbonyl)benzene;NSC 41884;188665-61-4;1640987-71-8
Categories:
Chemical Reagents > Organic Reagents

Request for Quotation

Description

white crystalline mass

DryPowder; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals

Isophthaloyl chloride Basic Attributes

Molecular Weight：

203.02

Exact Mass：

203.02

BRN：

638342

EC Number：

202-774-7

UNII：

6A3LDJ6CL3

NSC Number：

41884

DSSTox ID：

DTXSID3026641|DTXSID5094602|DTXSID90745711

Color/Form：

CRYSTALLINE SOLID|PRISMS FROM ETHER

HScode：

29173940

Characteristics

PSA：

34.1

XLogP3：

3.6

Appearance：

White Crystalline Mass

Density：

1.3880 g/cm³ @ Temp: 17 °C

Melting Point：

43-44 °C

Boiling Point：

276 °C

Flash Point：

356 °F

Refractive Index：

1.570 (47ºC)

Water Solubility：

Solubility in water: reaction

Storage Conditions：

Store below +30°C.

Vapor Pressure：

0.03 mm Hg ( 25 °C)

Toxicity：

Oral-rat LD50: 2200 mg/kg; Oral-Mouse LD50: 2221 mg/kg

Flammability characteristics：

Flammable; emit toxic hydrogen chloride gas in water

Explosive limit：

1.5-8.9%(V)

Experimental Properties：

REACTIVE WITH WATER & ALCOHOL

Safety Information

Packing level：

Hazard category：

Transport codes：

UN 3261 8/PG 2

wgk germany：

hazard class code：

21-34-37-35-23

safety instructions：

26-36/37/39-45-7/8-24/25

RTECS Number：

NT2625000

Marks：

C,T

Storage features：

The warehouse is ventilated, low temperature and dry; stored separately from alkali and oxidant

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P280, P302+P352, P312, P322, P363, P501

Hazard Statements：

H312

GHS Classification：

|Danger|H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]|P260, P261, P264, P271, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P312, P321, P322, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 238 companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Warning|H312: Harmful in contact with skin [Warning Acute toxicity, dermal]|P280, P302+P352, P312, P322, P363, and P501

Toxicity

Toxicity class：

practically nontoxic

Drug Information

Human Toxicity Excerpts：

IRRITANT TO EYES & SKIN.

MeSH Entry Terms：

1,3-benzenedicarbonyl chloride

Isophthaloyl chloride Use and Manufacturing

Methods of Manufacturing

There are thionyl chloride method, phosphorus pentachloride method, phosgene method, dimethyl isophthalate chlorination method, isophthalic acid chlorination method. The phosgene method is mostly used, and the phosgenation reaction is usually carried out in the presence of a formamide catalyst. If the isophthalic acid is first converted into the meta-anhydride, and then the phosgenation reaction, the isophthaloyl chloride itself is used as the reaction solvent, and a higher yield can be obtained.

Uses

Used as pesticide, medicine, polymer intermediate

Intermediates

Production

10,000,000 - 50,000,000 lb

Manufacturing Info：

1,3-Benzenedicarbonyl dichloride, homopolymer: INACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).|Adhesive manufacturing|1,3-Benzenedicarbonyl dichloride: ACTIVE

Computed Properties

Molecular Weight:203.02
XLogP3:3.6
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:201.9588348
Monoisotopic Mass:201.9588348
Topological Polar Surface Area:34.1
Heavy Atom Count:12
Complexity:183
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Isophthalic acid

Ethanol

Thionyl chloride

Recommended Suppliers of Isophthaloyl chloride

Farmasino Pharmaceutical Contact Supplier

CN
7 YRS

Business licensed Certified factory

Manufactory Supplier of Acesulfame k,Aspartame,BCAA(Keratin hydrolyzed),Beta-alanine,Citric Acid,Conjugated Linoleic Acid Powder,Creatine Monohydrate,Dextrose,Folic Acid,Inositol,L-Carnitine,L-Carnitine L-Tartrate,L-Glutamine,L-Valine,ManNeotamenitol,Potassium Sorbate,Sodium Benzoic,Saccharin sodium,Sodium Starch Glycolate,Stevioside,Sucralose,Vital Wheat Gluten,Vitamin B2,Vitamin C,Vitamin B12,Other chemical product

Isophthaloyl Dichloride & 1,3-benzenedicarboxylicacid

CAS No.: 99-63-8

Grade: Industrial Grade

Inquiry
Greenbo Biochem Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides,Organic Intermediates,OLED Intermediates

Isophthaloyl dichloride 99% high purity certified Professional Producer Greenbo

CAS No.: 99-63-8

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
NANTONG REFORM PETRO-CHEMICAL CO.,LTD Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals,Surfactant,Food Additives,Water Treatment Chemicals

Isophthaloyl dichloride

CAS No.: 99-63-8

Grade: Industrial Grade

Content: 99%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

High quality Isophthaloyl dichloride CAS NO.99-63-8

CAS No.: 99-63-8

Grade: Pharmaceutical Grade

Content: 99%

Inquiry