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Manool

Manool structure

Manool 

structure
  • CAS No:

    596-85-0

  • Formula:

    C20H34O

  • Chemical Name:

    Manool

  • Synonyms:

    1-Naphthalenepropanol,α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-,(αR,1S,4aS,8aS)-;Labda-8(20),14-dien-13-ol,(13R)-;Manool;1-Naphthalenepropanol,α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-,[1S-[1α(S*),4aβ,8aα]]-;(αR,1S,4aS,8aS)-α-Ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol;NSC 165961;Labd-8(17),14-dien-13-ol

Description

ChEBI: A labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13.

Manool Basic Attributes

290.491

290.48

637-366-1

DTXSID4022072

Characteristics

20.2

5.50240

0.93g/cm3

41-43.5 °C

150-153 °C @ Press: 0.3 Torr

118.2ºC

1.5

Safety Information

3

R36/37/38

S26-S36

Xi: Irritant;

P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, P501

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

(+)-manool

Manool Use and Manufacturing

Maintains anti-proliferative activity against human malignant cell strains.

Computed Properties

Molecular Weight:290.5
XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:290.260965704
Monoisotopic Mass:290.260965704
Topological Polar Surface Area:20.2
Heavy Atom Count:21
Complexity:422
Defined Atom Stereocenter Count:3
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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