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NEOMYCINSULFATE

NEOMYCINSULFATE structure
  • CAS No:

    1404-04-2

  • Formula:

    C23H52N6O25S3

  • Synonyms:

    neomas;neomin;neomcin;neolate;myacyne;NEOMYCIN;Jernadex;nivemycin;Bycomycin;Neomyacin

  • Categories:

    API  >  Antibiotics

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Basic Attributes

  • 1404-04-2

  • C23H52N6O25S3

  • 908.88

  • 614.312256

  • 602.05000

  • -3.65

  • 215-773-1

  • PGBHMTALBVVCIT-UHFFFAOYSA-N

  • 19

  • 13

  • 9

Characteristics

  • powder

  • 1.6±0.1 g/cm3

  • 927.1±65.0 °C at 760 mmHg

  • 514.5±34.3 °C

  • 1.675

  • H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days.

  • 2-8°C

  • 1.60X10-28 mm Hg at 25 °C (est)

  • Hygroscopic. /Neomycin sulfate/

Safety Information

  • 3

  • 42/43

  • 22-36/37-45

  • QP4375000

  • Xn

Usage

A broad-spectrum antibiotic with an antibacterial spectrum similar to kanamycin. Mainly for local application to treat various skin infections and ear infections caused by sensitive bacteria such as Staphylococcus aureus and Proteus

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Production Methods

Using Streptomyces fradiae as the strain, the fermentation broth is obtained by culturing and fermenting, after adding a strong acid cation exchange resin to adsorb, eluting with ammonia water, and then concentrating the eluate through a thin film, then spray drying in sulfuric acid. . Neomycin is a multi-component aminoglycoside antibiotic. The main components are neomycin B and C (mainly B), containing a trace amount of neomycin A (Neamine).

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