Polymyxin
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Polymyxin
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CAS No:
1406-11-7
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Chemical Name:
Polymyxin
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Synonyms:
Polymyxin;Polymixin;9063-10-9
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CAS No:
Description
All are basic polypeptides. Soluble in water; the hydrochlorides are soluble in water and methanol, insoluble in ether, acetone, chlorinated solvents, and hydrocarbons. Permissible food additives.Generic term for a series of antibiotic substances produced by strains of Bacillus polymyxa. Various polymyxins are differentiated by the letters A, B, C, D, and E. All are active against certain gram-negative bacteria. Polymyxin B is most used.
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
Drug Information
Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)
Polymyxin
Computed Properties
Molecular Weight:1107.3
XLogP3:-8
Hydrogen Bond Donor Count:19
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:23
Exact Mass:1106.61964135
Monoisotopic Mass:1106.61964135
Topological Polar Surface Area:511
Heavy Atom Count:78
Complexity:2010
Defined Atom Stereocenter Count:12
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
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Polymyxin E1, 1-de(N(sup 2)-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-2-(N-(phenoxyacetyl)-L-threonine)-, hydrochlorideCAS:52396-34-6Purity:98% HPLC Package:5mg;1G;10G;100G;1KG
52396-34-6
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polymyxin S(1)
63700-38-9
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Polymyxin D
1404-29-1
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Polymyxin B1, 1-(L-2,4-diaminobutanoic acid)- Formula
76014-40-9
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Polymyxin E1,1-de(N(sup 2)-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid)-2-(N-(1-oxohexyl)-L-threonine)-,hydrochloride Formula
51887-95-7
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polymyxin T(1) Formula
63700-39-0
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Polymyxin B Structure
1404-26-8
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polymyxin B cyclononapeptide Structure
86408-36-8
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What is Polymyxin B, N-sulfomethyl deriv., sodium salt
1407-09-6
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What is pelargonoyl cyclic decapeptide polymyxin M(1)
77554-83-7