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1-Aminopyrene

1-Aminopyrene structure

1-Aminopyrene 

structure
  • CAS No:

    1606-67-3

  • Formula:

    C16H11N

  • Chemical Name:

    1-Aminopyrene

  • Synonyms:

    1-Pyrenamine;3-Aminopyrene;1-Aminopyrene;α-Aminopyrene;NSC 11436;1-Aminopyren;1087757-03-6

  • Categories:

    Chemical Reagents  >  Organic Reagents

Description

yellow-green powderColorless crystals. Yellow needles from hexane, melting point 117-8°C.


1-aminopyrene appears as colorless crystals. Yellow needles from hexane, melting point 117-118°C.|Solid


1-aminopyrene appears as colorless crystals. Yellow needles from hexane, melting point 117-118°C.

1-Aminopyrene Basic Attributes

217.27

217.27

216-521-3

LUW9EO1681

11436

DTXSID3040932

29214990

Characteristics

26

4.3

Yellow to green Powder

1.1227 (rough estimate)

115-117 °C

347.82°C (rough estimate)

246.2±15.4 °C

1.8230 (estimate)

Insoluble in water (0.576 mg/L at 25 deg C).

5.71E-08mmHg at 25°C

No rapid reaction with air. No rapid reaction with water.

Hydrocarbons, Aromatic

1-AMINOPYRENE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Safety Information

NONH for all modes of transport

3

22-40-21/22

45-36/37

UR2275000

Xn

Stable. Incompatible with strong oxidizing agents.

P280

H302-H312

This compound is probably combustible. (NTP, 1992)

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 44 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this material can be controlled with a dry chemical, carbon dioxide, foam or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should keep this material in a tightly-closed container under an inert atmosphere, and store it in a freezer. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Drug Information

1-aminopyrene has known human metabolites that include N-hydroxy-1-aminopyrene.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

1-aminopyrene

1-Aminopyrene Use and Manufacturing

Uses

It acts as a precursor molecule for production of other fluorescent probes such as 1-Azidopyrene, APTS, and N-(1-Pyrene)iodoacetamide.

1-Pyrenamine: ACTIVE

Computed Properties

Molecular Weight:217.26
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:217.089149355
Monoisotopic Mass:217.089149355
Topological Polar Surface Area:26
Heavy Atom Count:17
Complexity:300
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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