Methanesulfonic acid, 2-phenylethyl ester

General procedure: To a solution of corresponding alcohol (12A-B) or (15A-B) or (17A-B) or (19A-B) or (23A-B) (2.14 mmol) and triethylamine (0.36 mL, 2.59 mmol) in anhydrous dichloromethane (6 mL), kept to 0 °C, was added mesyl chloride (0.18 mL, 2.31 mmol). The reaction was maintained at 0 °C during the first hour, followed by warming to room temperature, under vigorous stirring and nitrogen atmosphere for 3 h. At the end of this time the solution was extracted with dichloromethane (3 .x. 30 mL) and the combined organic extracts were washed with a 10percent aqueous hydrochloric acid solution, brine, dried over sodium sulfate and evaporated. The obtained residue was separated by chromatography on silica gel eluted with dichloromethane, followed by chloroform to give the desired O-mesylated derivatives, as described in Supplementary Material.General procedure: To a flask that was charged with the benzyl alcohol (10 mmol), triethylamine (20 mmol) in THF (25 mL) cooled at 0 °C, was added mesyl chloride (20 mmol) in THF (50 mL) over half an hour. Then the mixture was allowed to stir at room temperature for about 20-30 min. Cold water was added to the mixture, then the mixture was extracted with diethyl ether (125 mLx1). Triethylamine (5 mol) was added into the crude product solution to remove the unreacted mesyl chloride. Then the solution was washed with saturated aqueous NaHCO

Molecular Weight:200.26
XLogP3:1.6
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:200.05071541
Monoisotopic Mass:200.05071541
Topological Polar Surface Area:51.8
Heavy Atom Count:13
Complexity:222
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes