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Methyltryptamine

Methyltryptamine structure

CAS No:
61-49-4
Formula:
C11H14N2
Chemical Name:
Methyltryptamine
Synonyms:
1H-Indole-3-ethanamine,N-methyl-;Indole,3-[2-(methylamino)ethyl]-;N-Methyl-1H-indole-3-ethanamine;Dipterine;Methyltryptamine;N-Methyltryptamine;Nb-Methyltryptamine;Monomethyltryptamine;N-Monomethyltryptamine;Nω-Methyltryptamine;3-(2-Methylaminoethyl)indole;3-[2-(Methylamino)ethyl]-1H-indole;N10-Methyltryptamine;[2-(1H-Indol-3-yl)ethyl]methylamine;2-(1H-Indol-3-yl)-N-methylethanamine
Categories:
Organic Chemistry > Amides

Description

white to off-white shiny cryst. powder or flakes

Solid

N-methyltryptamine is a tryptamine alkaloid and a member of tryptamines. It has a role as a metabolite. It derives from a tryptamine.

Methyltryptamine Basic Attributes

Molecular Weight：

174.242

Exact Mass：

174.24

EC Number：

200-507-9

UNII：

6FRL4L3Z7V

DSSTox ID：

DTXSID70209846

HScode：

2933990090

Characteristics

PSA：

27.82000

XLogP3：

1.52

Appearance：

Solid

Density：

1.1±0.1 g/cm3

Melting Point：

90 °C

Boiling Point：

160-170 °C @ Press: 0.01 Torr

Flash Point：

157.1±20.9 °C

Refractive Index：

1.621

Water Solubility：

>26.1 [ug/mL]

Collision Cross Section：

142.5 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|142.8 Å² [M+H]+

Safety Information

wgk germany：

safety instructions：

S24/25

RTECS Number：

NM0450000

Drug Information

MeSH Entry Terms：

2-(1H-indol-3-yl)-N-methylethanamine

Methyltryptamine Use and Manufacturing

Reactant for preparation of:• ;Manzamine analogues for the control of neuroinflammation and cerebral infections1• ;Serotonin 4 receptors (5-HT4) receptor agonists2• ;A sulful-containing indole alkaloid, glypetelotine3• ;Selective inhibitors of cyclin dependent kinase (CDK4)4• ;Antagonist of the human tachykinin NK-2 receptor5• ;Inhibitors of the tyrosine-specific protein kinase pp60c-src SH2 Domain6 N-Methyltryptamine (NMT) is a naturally-occurring tryptamine which may be derived from L-tryptophan or, indirectly, from serotonin. While substituted NMTs are psychoactive through their effects on monoamine action, NMT appears to be rapidly metabolized by monoamine oxidases. This product is intended for research and forensic applications.[Cayman Chemical]

Computed Properties

Molecular Weight:174.24
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:174.115698455
Monoisotopic Mass:174.115698455
Topological Polar Surface Area:27.8
Heavy Atom Count:13
Complexity:158
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes