 Home > Encyclopedia > Moroxydine

Moroxydine

Moroxydine structure

CAS No:
3731-59-7
Formula:
C6H13N5O
Chemical Name:
Moroxydine
Synonyms:
4-Morpholinecarboximidamide,N-(aminoiminomethyl)-;4-Morpholinecarboxamidine,N-amidino-;Guanidine,4-morpholinecarboximidoyl-;N-(Aminoiminomethyl)-4-morpholinecarboximidamide;JD 1022;N1,N1-Anhydrobis(β-hydroxyethyl)biguanide;Moroxydine;4-Morpholinecarboximidoylguanidine;Vironil;Virugon;Virumin;Wirumin;ABOB;SKF 8898A;N-[Imino(4-morpholinyl)methyl]guanidine;22088-30-8;1195864-29-9
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

N-(diaminomethylidene)-4-morpholinecarboximidamide is a member of biguanides.|Moroxydine is a heterocyclic biguanidine with activity against influenza and other viral infections. Although its mechanism of action is not fully known the effects seem to be due to an influence on the virus host-cell system.

Moroxydine Basic Attributes

Molecular Weight：

171.2

Exact Mass：

171.20

EC Number：

223-093-1

UNII：

O611591WAH

DSSTox ID：

DTXSID3048526

NCI Thesaurus Code：

C66200

ATC Code：

J - Antiinfectives for systemic use

HScode：

2934999090

Characteristics

PSA：

101

XLogP3：

-1.6

Density：

1.51 g/cm3

Melting Point：

196-198 °C

Boiling Point：

327ºC at 760 mmHg

Flash Point：

151.6ºC

Refractive Index：

1.661

Safety Information

Hazard category：

IRRITANT

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-37/39-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

MeSH Entry Terms：

4-morpholinocarboximidoylguanidine

Moroxydine Use and Manufacturing

antiviral

Computed Properties

Molecular Weight:171.20
XLogP3:-1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:171.11201006
Monoisotopic Mass:171.11201006
Topological Polar Surface Area:101
Heavy Atom Count:12
Complexity:192
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Morpholine

Dicyandiamide

Ethanol

Activated charcoal

Hydrochloric acid

Drug Function and Efficacy

Not yet clear

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Zhiganjia Capsules
Ingredients	Sesame, Andrographis paniculata, Calabash tea, Trichosanthes, Radix Isatidis, Notopterygium wilfordii, Menthol, Paracetamol, Morphoguanidine hydrochloride, Chlorpheniramine maleate.
Indication	Not yet clear
Specifications	Each tablet contains 100mg of acetaminophen
Manufacturer	Tonghua Baixin Pharmaceutical Co., Ltd.

Zhiganjia Tablets
Ingredients	Sesame, Andrographis paniculata, Calabash tea, Trichosanthes kirilowii, Isatis root, Notopterygium wilfordii, Menthol, Acetaminophen, Morphoguanidine hydrochloride, Chlorpheniramine maleate.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each tablet contains 50mg of acetaminophen
Manufacturer	Zhaoqing Xinghu Pharmaceutical Co., Ltd.

Zhiganjia Capsules
Ingredients	Sesame, Andrographis paniculata, Calabash tea, Trichosanthes, Radix Isatidis, Notopterygium wilfordii, Menthol, Paracetamol, Morphoguanidine hydrochloride, Chlorpheniramine maleate.
Indication	Not yet clear
Specifications	Each tablet contains 0.1g of acetaminophen
Manufacturer	Shijiazhuang Kedi Pharmaceutical Co., Ltd.

See More Related Drugs