 Home > Encyclopedia > 2-Fluoro-3-pyridinecarbonitrile

2-Fluoro-3-pyridinecarbonitrile

2-Fluoro-3-pyridinecarbonitrile structure

CAS No:
3939-13-7
Formula:
C6H3FN2
Chemical Name:
2-Fluoro-3-pyridinecarbonitrile
Synonyms:
3-Pyridinecarbonitrile,2-fluoro-;Nicotinonitrile,2-fluoro-;2-Fluoro-3-pyridinecarbonitrile;2-Fluoronicotinonitrile;3-Cyano-2-fluoropyridine
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Request for Quotation

2-Fluoro-3-pyridinecarbonitrile Basic Attributes

Molecular Weight：

122.1

Exact Mass：

122.10

BRN：

386567

EC Number：

2017-001-1

DSSTox ID：

DTXSID40382539

HScode：

29333990

Characteristics

PSA：

36.7

XLogP3：

Density：

1.2±0.1 g/cm3

Melting Point：

30 °C

Boiling Point：

214.6°C at 760 mmHg

Flash Point：

98℃

Refractive Index：

1.510

Safety Information

Packing level：

III

Hazard category：

6.1

Transport codes：

3276

wgk germany：

hazard class code：

20/21/22-36/37/38-5-36/38-22

safety instructions：

26-36/37/39-36-24/25-23-3

Marks：

Xi,Xn

Hazard note：

Harmful/Irritant

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H302-H315-H319

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 45 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Fluoro-3-pyridinecarbonitrile Use and Manufacturing

General procedure: To a solution of 2, 3-dichloropyridine(1.00 g, 6.76 mmol) in DMSO (33.8 ml) was added CsF (2.053 g, 13.51mmol) at room temperature. The mixture was stirred at 110 °C under air for 20h. The mixture was quenched with water at room temperature and extracted withEtOAc. The organic layer was separated, washed with water and brine, dried overNaPreparation 51; 2-Fluoro-nicotinonitrile; Add resin bound triphenylphosphine (4.0 g, 12.0 mmol) to a solution of 2-fluoro- nicotinamide (0.6 g, 4.3 mmol) in dichloroethane (20.0 mL) and carbon tetrachloride (20.0 mL). Reflux for 18 hours, cool to RT, filter, and concentrate the filtrate under vacuum. Purify by flash column on silica gel eluting with 10-60percent EtOAc in hexanes to give the title compound (0.34 g, 64percent). MS (ES) 123.1 (M+l) +. 1H NMR (400 MHz, CHC13) 6 8.46 (m, 1H), 8.09 (m, 1H), 7.37 (m, 1H).To a 20 mL scintillation vial was added

Computed Properties

Molecular Weight:122.10
XLogP3:1
Hydrogen Bond Acceptor Count:3
Exact Mass:122.02802627
Monoisotopic Mass:122.02802627
Topological Polar Surface Area:36.7
Heavy Atom Count:9
Complexity:137
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Fluoro-3-pyridinecarbonitrile

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

3-Cyano-2-fluoropyridine

CAS No.: 3939-13-7

Content: 99.00%

Inquiry

Latest News on 2-Fluoro-3-pyridinecarbonitrile

Learn More Other Chemicals

(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID

51485-76-8
Benadryl N-oxide hydrochloride

13168-00-8
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE

885275-59-2
(2-Bromophenyl)diphenylphosphine Formula

62336-24-7
1-Morpholinocyclopentene Formula

936-52-7
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula

168892-66-8
3-amino-5-bromopyridine-2-carboxylic acid Structure

870997-85-6
2-Amino-6-methylpyridine Structure

1824-81-3
What is 3-Bromo-2-methylthiophene

30319-05-2
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER

2026-42-8

Hot Searches: potassium sulfide; phosphoric acid formula; tert-butyl alcohol; menthone ghs symbol; lacunar stroke; remeron generic name

Guide of 2-Fluoro-3-pyridinecarbonitrile

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

2-Fluoro-3-pyridinecarbonitrile

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.