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Diphenoxylate hydrochloride

Diphenoxylate hydrochloride structure

Diphenoxylate hydrochloride 

structure
  • CAS No:

    3810-80-8

  • Formula:

    C30H32N2O2.ClH

  • Chemical Name:

    Diphenoxylate hydrochloride

  • Synonyms:

    4-Piperidinecarboxylic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,ethyl ester,hydrochloride (1:1);Isonipecotic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,ethyl ester,monohydrochloride;4-Piperidinecarboxylic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,ethyl ester,monohydrochloride;Isonipecotic acid,1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,ethyl ester,hydrochloride;1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride;Diphenoxylate hydrochloride;2,2-Diphenyl-4-(4-carbethoxy-4-phenyl-1-piperidino)butyronitrile hydrochloride;2,2-Diphenyl-4-(4-carboxy-4-phenyl-1-piperidino)butyronitrile ethyl ester hydrochloride;R 1132;R 1132 (antiperistaltic)

  • Categories:

    Analytical Chemistry  >  Standard

Description

White or almost white, crystalline powder.

Diphenoxylate hydrochloride Basic Attributes

489.05

488.223053

223-287-6

2933330000

Characteristics

53.33000

6.22318

220.5-222 °C

602.3ºC at 760mmHg

318ºC

Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).

-20°C

Oral-Rat  LD50:  221 mg/kg; Abdominal cavity-mouse LD50: > 320 mg/kg

Flammable, decomposes toxic nitrogen oxides and chloride gases when burned

Safety Information

III

6.1(b)

1544

Treasury is low temperature, ventilated, dry; stored separately from food raw materials

P260, P261, P262, P264, P270, P271, P272, P280, P284, P285, P301+P310, P302+P350, P302+P352, P304+P340, P304+P341, P310, P320, P321, P322, P330, P333+P313, P342+P311, P361, P363, P403+P233, P405, P501

H300

Toxicity

highly toxic

Diphenoxylate hydrochloride Use and Manufacturing

Antiperistaltic; antidiarrheal. Controlled substance (opiate).

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