16α-Hydroxyprogesterone
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16α-Hydroxyprogesterone
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CAS No:
438-07-3
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Formula:
C21H30O3
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Chemical Name:
16α-Hydroxyprogesterone
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Synonyms:
Pregn-4-ene-3,20-dione,16-hydroxy-,(16α)-;Pregn-4-ene-3,20-dione,16α-hydroxy-;(16α)-16-Hydroxypregn-4-ene-3,20-dione;16α-Hydroxy-Δ4-pregnene-3,20-dione;16α-Hydroxyprogesterone;16α-Hydroxy-4-pregnene-3,20-dione;NSC 523249;NSC 53910
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CAS No:
Description
16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone. 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.
16alpha-hydroxyprogesterone is a 16alpha-hydroxy steroid. It derives from a progesterone.
Characteristics
54.4
3.69430
1.15g/cm3
225-226 °C
487.4ºC at 760mmHg
262.7ºC
1.557
1.51E-11mmHg at 25°C
16α-Hydroxyprogesterone Use and Manufacturing
16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.
Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives [ST0203]
Computed Properties
Molecular Weight:330.5
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:330.21949481
Monoisotopic Mass:330.21949481
Topological Polar Surface Area:54.4
Heavy Atom Count:24
Complexity:621
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes