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Coniferaldehyde

Coniferaldehyde structure

Coniferaldehyde 

structure
  • CAS No:

    458-36-6

  • Formula:

    C10H10O3

  • Chemical Name:

    Coniferaldehyde

  • Synonyms:

    2-Propenal,3-(4-hydroxy-3-methoxyphenyl)-;Cinnamaldehyde,4-hydroxy-3-methoxy-;3-(4-Hydroxy-3-methoxyphenyl)-2-propenal;Coniferaldehyde;Ferulaldehyde;p-Coniferaldehyde;4-Hydroxy-3-methoxycinnamaldehyde;Coniferyl aldehyde;3-Methoxy-4-hydroxycinnamaldehyde;3-(4-Hydroxy-3-methoxyphenyl)acrolein;Ferulyl aldehyde;2-Methoxy-4-(3-oxo-1-propenyl)phenol;4-Hydroxy-3-methoxyzimtaldehyde;3-(4-Hydroxy-3-methoxyphenyl)propenal;Ferulic aldehyde

Description

Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

Coniferaldehyde Basic Attributes

178.187

178.18

207-278-4

DTXSID8075047

2912499000

Characteristics

46.5

1.35

1.1562 g/cm3 @ Temp: 101.5 °C

84 °C

169 °C @ Press: 4 Torr

136.8±17.2 °C

1.593

4.88E-05mmHg at 25°C

Safety Information

NONH for all modes of transport

3

36/37/38

26-37/39

Xi: Irritant;

P261-P305 + P351 + P338

H315-H319-H335

Drug Information

ferulaldehyde

Computed Properties

Molecular Weight:178.18
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:178.062994177
Monoisotopic Mass:178.062994177
Topological Polar Surface Area:46.5
Heavy Atom Count:13
Complexity:189
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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