2-Methoxyethanol
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2-Methoxyethanol
structure -
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CAS No:
109-86-4
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Formula:
C3H8O2
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Chemical Name:
2-Methoxyethanol
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Synonyms:
Ethanol,2-methoxy-;2-Methoxyethanol;Dowanol EM;Ethylene glycol methyl ether;Ethylene glycol monomethyl ether;Glycol methyl ether;Glycol monomethyl ether;Methoxyhydroxyethane;Methyl glycol;Methyl oxitol;Poly-Solv EM;Methyl Cellosolve;Methoxyethanol;Methoxyethylene glycol;β-Methoxyethanol;1-Hydroxy-2-methoxyethane;2-Methoxy-1-ethanol;Monomethylglycol;Ektasolve EM;2-Methoxyethyl alcohol;3-Oxa-1-butanol;Monoethylene glycol methyl ether;Amsco-Solv EE;2-Methyloxyethanol;NSC 1258;Hisolve MC
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CAS No:
Description
2-Methoxyethanol is a colorless liquid with a slight ethereal odor. The Odor Threshold is 0.92.3 ppm. It is miscible with water and with aliphatic and aromatic hydrocarbons. It is a solvent for essential oils, lignin, dammar, Elemi Essential Oil, ester gum, kauri, mastic, rosin, sandarac resin, shellac, Zanzibar, nitrocellulose, cellulose acetate, alcohol-soluble dyes and many synthetic resins. Its solvency far cellulose esters is augmented when a ketone or a halogenated hydrocarbon i s added.
Characteristics
29.46000
-0.37490
Ethylene glycol monomethyl ether appears as a clear colorless liquid. Flash point of 110°F. Less dense than water. Vapors are heavier than air.
0.96 g/cm3
-85.1 °C
124.1 °C
38ºC
1.402
H2O: soluble
5ºC
6.17 mm Hg ( 20 °C)
2.62 (vs air)
LD50 in rats, guinea pigs (mg/kg): 2460, 950 orally (Smyth); LC50 (7 hr in air) in mice: 4.6 mg/l (Werner)
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
vol% in air: 2.34.5
Mild agreeable odor
Bitter
14.8(at 25 °C)
Safety Information
III
3
UN 1188
3
R10; R20/21/22; R60; R61
S45-S53
ZC0110000
T
Fireproof. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Cool.
Stable, but contact with air may lead to the formation of explosive peroxides.
P201-P210-P260-P280-P308 + P311-P370 + P378
H226-H302 + H312 + H332-H360FD-H370-H373
2-Methoxyethanol Use and Manufacturing
2-Methoxyethanol, or methyl cellosolve, is an organic compound with formula C 3H 8O 2 that is used mainly as a solvent. It is a clear, colorless liquid with an ether-like odor. It is in a class of solvents known as glycol ethers which are notable for their ability to dissolve a variety of different types of chemical compounds and for their miscibility with water and other solvents. It can be formed by the nucleophilic attack of methanol on protonated oxirane followed by proton transfer: C 2H 5O+ + CH 3OH → C 3H 8O 2 + H+ 2-Methoxyethanol is used as a solvent for many different purposes such as varnishes, dyes, and resins. It is also used as an additive in airplane deicing solutions. In organometallic chemistry it is commonly used for the synthesis of Vaska's complex and related compounds such as carbonylchlorohydridotris(triphenylphosphine)ruthenium (II). During these reactions the alcohol acts as a source of hydride and carbon monoxide.2-Methoxyethanol is toxic to the bone marrow and testicles. Workers exposed to high levels are at risk for granulocytopenia, macrocytic anemia, oligospermia, and azoospermia.The methoxyethanol is converted by alcohol dehydrogenase into methoxyacetic acid which is the substance which causes the harmful effects. Both ethanol and acetate have a protecting effect. The methoxyacetate can enter the Krebs cycle where it forms methoxycitrate.
Computed Properties
Molecular Weight:76.09
XLogP3:-0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:76.052429494
Monoisotopic Mass:76.052429494
Topological Polar Surface Area:29.5
Heavy Atom Count:5
Complexity:14.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Price Analysis
- Data: 2026-07-21
- Price: 8500.00Yuan/mt
- Change: 325.0
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