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Ophiobolin A

Ophiobolin A structure

CAS No:
4611-05-6
Formula:
C25H36O4
Chemical Name:
Ophiobolin A
Synonyms:
Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde,1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propen-1-yl)-7-oxo-,(2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-;Ophiobola-7,19-dien-25-al,14,18-epoxy-3-hydroxy-5-oxo-,(18R)-;Ophiobolin;Cochliobolin A;Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde,1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propenyl)-7-oxo-,(2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-;(2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-Dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde;Ophiobolin A;Cochliobolin;Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde,1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propenyl)-7-oxo-,[3S-[3α(3′R*,5′S*),3aα,6aβ,9α,9aβ,10aβ]]-;NSC 114340;(+)-Ophiobolin A;1347-57-5;5843-70-9;11022-22-3;17046-71-8

Description

Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase, with an IC50 value of 9 μM. Ophiobolin A antimicrobial and anticancer activity[1].

Ophiobolin A Basic Attributes

Molecular Weight：

400.551

Exact Mass：

400.55

Characteristics

PSA：

63.60000

XLogP3：

3.75

Density：

1.1±0.1 g/cm3

Melting Point：

181-182 °C

Boiling Point：

539.4±50.0 °C at 760 mmHg

Flash Point：

177.8±23.6 °C

Refractive Index：

1.554

Safety Information

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

20/21/22

safety instructions：

S36

RTECS Number：

RL1576000

Marks：

Precautionary statement(s)：

Missing Phrase - N15.00950417-P261-P280

Hazard Statements：

H301-H312 + H332

Ophiobolin A Use and Manufacturing

Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi. Ophiobolin A acts by inhibiting calmodulin action in calcium regulation.

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Guide of Ophiobolin A

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Learn More Other Chemicals

Ophiobolin A

SDS

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