(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one
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(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one
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CAS No:
4927-26-8
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Formula:
C22H34O3
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Chemical Name:
(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one
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Synonyms:
Pregn-5-en-20-one,3,17-dihydroxy-16-methyl-,(3β,16α)-;Pregn-5-en-20-one,3β,17-dihydroxy-16α-methyl-;(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one;NSC 63321;478614-19-6
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CAS No:
(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one Basic Attributes
346.50356
346.50
225-557-9
63321
DTXSID60197748
(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one Use and Manufacturing
Available 3β-hydroxyprogesterone-5, 16-diene-20-one-3-acetate, (ie pregnancy dienolone acetate), via (16-position double bond and nitrosomethylurea) Addition and elimination to produce 3β-hydroxy-16β-methylpregna-5, 16-diene-20-one-3-acetate, which is then epoxidized by (16-position double bond), (epoxy group) ) Ring opening (forming 17α-hydroxyl and 15-position double bond), (15-position double bond) catalytic hydrogenation, hydrolysis (de 3-position acetyl group) to prepare the product.
Intermediate of dexamethasone acetate.
Computed Properties
Molecular Weight:346.5
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:346.25079494
Monoisotopic Mass:346.25079494
Topological Polar Surface Area:57.5
Heavy Atom Count:25
Complexity:625
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
(3β,16α)-3,17-Dihydroxy-16-methylpregn-5-en-20-one
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