(-)-Eburnamonine
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(-)-Eburnamonine
structure -
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CAS No:
4880-88-0
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Formula:
C19H22N2O
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Chemical Name:
(-)-Eburnamonine
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Synonyms:
Eburnamenin-14(15H)-one,(3α,16α)-;Vincamone;1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine,eburnamenin-14(15H)-one deriv.;(3α,16α)-Eburnamenin-14(15H)-one;(3α,16α)-Eburnamonine;(-)-Eburnamonine;(-)-Vincamone;l-Eburnamonine;cis-Vincamone;(-)-cis-Eburnamonine;Eburnal Ritardo;Vinburnine;16-Oxoeburnane;Cervoxan;CH 846;13090-13-6;412037-03-7
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CAS No:
Description
Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
Eburnamonine is an alkaloid.
(-)-Eburnamonine Basic Attributes
294.39
294.39
225-490-5
G54D0HMY25
322920
DTXSID6045119
C - Cardiovascular system
2933990090
Characteristics
25.2
3.71250
white powder
1.3±0.1 g/cm3
168-170 °C
441.9°C at 760 mmHg
221.0±25.4 °C
1.719
D25 -102° (chloroform) (Clauder); D -100° (c = 0.783 in chloroform) (Cartier)
Safety Information
Ⅲ
2811
2
6.1
22-24/25
YY8575570
|Warning|H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]|P260, P314, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)
(-)-eburnamonine
(-)-Eburnamonine Use and Manufacturing
Cerebral vasodilatator Vincabonin, also called ivory ketone, is white or light yellow crystalline powder at room temperature. Vinblastine is used as a cerebral vasodilator, which has a more pronounced vasodilation effect than vinblastine, and can promote oxygen consumption and the brain's utilization of glucose. As clinically used to treat ischemic stroke and other diseases caused by cerebrovascular disease, it has great significance in clinical application.
Computed Properties
Molecular Weight:294.4
XLogP3:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:294.173213330
Monoisotopic Mass:294.173213330
Topological Polar Surface Area:25.2
Heavy Atom Count:22
Complexity:492
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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