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Home > Encyclopedia > 4-Hydroxycyclophosphamide

4-Hydroxycyclophosphamide

4-Hydroxycyclophosphamide structure

4-Hydroxycyclophosphamide 

structure
  • CAS No:

    40277-05-2

  • Formula:

    C7H15Cl2N2O3P

  • Chemical Name:

    4-Hydroxycyclophosphamide

  • Synonyms:

    2H-1,3,2-Oxazaphosphorin-4-ol,2-[bis(2-chloroethyl)amino]tetrahydro-,2-oxide;4-Hydroxycyclophosphamide;Asta 6635;NSC 196562;2-[Bis(2-chloroethyl)amino]tetrahydro-4-hydroxy-2H-1,3,2-oxazaphosphorine 2-oxide;2-[Bis(2-chloroethyl)amino]-4-hydroxy-1,3,2λ5-oxazaphosphinan-2-one

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

ChEBI: A phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen.


4-hydroxycyclophosphamide is a phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen. It has a role as an alkylating agent and a metabolite. It is a nitrogen mustard, an organochlorine compound and a phosphorodiamide.

4-Hydroxycyclophosphamide Basic Attributes

277.082

277.09

196562

DTXSID50857748

Characteristics

61.8

0.2

Drug Information

4-hydroxycyclophosphamide

Computed Properties

Molecular Weight:277.08
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:276.0197347
Monoisotopic Mass:276.0197347
Topological Polar Surface Area:61.8
Heavy Atom Count:15
Complexity:238
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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