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Sesamolin

Sesamolin structure

CAS No:
526-07-8
Formula:
C20H18O7
Chemical Name:
Sesamolin
Synonyms:
1,3-Benzodioxole,5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-;Sesamolin;1H,3H-Furo[3,4-c]furan,tetrahydro-1-[3,4-(methylenedioxy)phenoxy]-4-[3,4-(methylenedioxy)phenyl]-,(1R,3aR,4S,6aR)-;1,3-Benzodioxole,5-[4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-,[1S-(1α,3aα,4α,6aα)]-;1,3-Benzodioxole,5-[4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-,(1S,3aR,4R,6aR)-;1H,3H-Furo[3,4-c]furan,1,3-benzodioxole deriv.;5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole;2-(3,4-Methylenedioxyphenoxy)-6-(3,4-methylenedioxyphenyl)-cis-3,7-dioxabicyclo[3.3.0]octane;Tetrahydro-1-[3,4-(methylenedioxy)phenoxy]-4-[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan;(+)-Sesamolin
Categories:
Analytical Chemistry > Standard

Description

Sesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression[1][2][3][4].

Sesamolin is a member of benzodioxoles.

Sesamolin Basic Attributes

Molecular Weight：

370.35

Exact Mass：

370.35

UNII：

7A90TJ149G

HScode：

29329990

Characteristics

PSA：

64.6

XLogP3：

2.88

Density：

1.4±0.1 g/cm3

Melting Point：

93.5 °C

Boiling Point：

520.8±50.0 °C at 760 mmHg

Flash Point：

219.2±30.0 °C

Refractive Index：

1.622

Specific rotation：

D20 +212° (chloroform)

Safety Information

Precautionary statement(s)：

P261, P272, P280, P302+P352, P321, P333+P313, P363, P501

Hazard Statements：

H317

Drug Information

MeSH Entry Terms：

sesamolin

Sesamolin Use and Manufacturing

Synergist for pyrethrum insecticides.

Computed Properties

Molecular Weight:370.4
XLogP3:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:370.10525291
Monoisotopic Mass:370.10525291
Topological Polar Surface Area:64.6
Heavy Atom Count:27
Complexity:544
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

CAS No.: 526-07-8

Content: 99.00%

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Sesamolin

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CAS No.: 526-07-8

Grade: Pharmaceutical grad

Content: 99%

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