Butacaine
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Butacaine
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CAS No:
149-16-6
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Formula:
C18H30N2O2
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Chemical Name:
Butacaine
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Synonyms:
1-Propanol,3-(dibutylamino)-,1-(4-aminobenzoate);Butacaine;1-Propanol,3-(dibutylamino)-,p-aminobenzoate (ester);1-Propanol,3-(dibutylamino)-,4-aminobenzoate (ester);1-Propanol,3-(dibutylamino)-,p-aminobenzoate;3-(p-Aminobenzoxy)-1-di-n-butylaminopropane;Butyn;3-(Dibutylamino)-1-propanol p-aminobenzoate;3-Dibutylaminopropyl p-aminobenzoate;Butelline
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CAS No:
Description
Butacaine is a local anesthetic.
4-aminobenzoic acid 3-(dibutylamino)propyl ester is a benzoate ester.
Characteristics
55.6
4.29910
1.0593 (rough estimate)
<25 °C
180 °C
219.9ºC
1.5700 (estimate)
>46 [ug/mL]
−20°C
6.1E-08mmHg at 25°C
Subcutaneous-rat LDL0: 150 mg/kg; subcutaneous-mouse LDL0: 100 mg/kg
Flammable; burning produces toxic nitrogen oxide gas
179 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
III
6.1(b)
3249
3
UB0875000
Treasury is ventilated, low temperature and dry; stored separately from food materials
Drug Information
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)
3-(dibutylamino)propyl 4-aminobenzoate
Computed Properties
Molecular Weight:306.4
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:12
Exact Mass:306.230728204
Monoisotopic Mass:306.230728204
Topological Polar Surface Area:55.6
Heavy Atom Count:22
Complexity:281
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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