Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > N,N-Bis(2-chloroethyl)phosphoramidic dichloride

N,N-Bis(2-chloroethyl)phosphoramidic dichloride

N,N-Bis(2-chloroethyl)phosphoramidic dichloride structure

N,N-Bis(2-chloroethyl)phosphoramidic dichloride 

structure
  • CAS No:

    127-88-8

  • Formula:

    C4H8Cl4NOP

  • Chemical Name:

    N,N-Bis(2-chloroethyl)phosphoramidic dichloride

  • Synonyms:

    Phosphoramidic dichloride,N,N-bis(2-chloroethyl)-;Phosphoramidic dichloride,bis(2-chloroethyl)-;N,N-Bis(2-chloroethyl)phosphoramidic dichloride;(N,N-Di-2-chloroethyl) phosphoramidic dichloride;Bis(2-chloroethyl)phosphoramidic dichloride;N,N-Bis(2-chloroethyl)phosphamide dichloride;Bis(2-chloroethyl)aminophosphoric dichloride;Bis(2-chloroethyl)aminophosphoryl dichloride;NSC 64119;2-Chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine;127025-92-7;1195248-43-1;2121600-95-9

N,N-Bis(2-chloroethyl)phosphoramidic dichloride Basic Attributes

258.898181

258.90

1312995-182-4

64119

DTXSID40155366

2931900090

Characteristics

30.12000

3.35170

1.509g/cm3

56 °C

127 °C @ Press: 2 Torr

138.2ºC

1.501

0.000847mmHg at 25°C

Safety Information

II

8

1759

|Danger|H301 (97.44%): Toxic if swallowed [Danger Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P312, P321, P322, P330, P333+P313, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

N,N-Bis(2-chloroethyl)phosphoramidic dichloride Use and Manufacturing

Methods of Manufacturing

It is chlorinated with diethanolamine with thionyl chloride to produce N, N-bis(chloroethyl)amine hydrochloride, which is then condensed with phosphorus oxychloride to obtain the product.

Uses

An intermediate for the synthesis of antitumor drugs used in chemotherapy

Computed Properties

Molecular Weight:258.9
XLogP3:2.4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:258.906812
Monoisotopic Mass:256.909762
Topological Polar Surface Area:20.3
Heavy Atom Count:11
Complexity:143
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.