Dipropylamine
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Dipropylamine
structure -
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CAS No:
142-84-7
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Formula:
C6H15N
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Chemical Name:
Dipropylamine
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Synonyms:
1-Propanamine,N-propyl-;Dipropylamine;N-Propyl-1-propanamine;Di-n-propylamine;n-Dipropylamine;Dipropanamine;N,N-Dipropylamine;N,N-Di(n-propyl)amine
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CAS No:
Description
Liquid
Dipropylamine is a flammable, highly toxic, corrosive amine. It occurs naturally in tobacco leaves and artificially in industrial wastes. Exposure can cause excitement followed by depression, internal bleeding, dystrophy, and severe irritation
Dipropylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.|Liquid
Dipropylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.
Dipropylamine Basic Attributes
101.19
101.19
505974
205-565-9
60P318IIRY
2383
DTXSID2025185
Colorless liquid|Water-white liquid
2921191000
Characteristics
12
1.67
Clear Liquid
0.738 g/cm3 @ Temp: 20 °C
-63 °C
109.3 °C
39 °F
1.405
H2O: soluble
Flammables area
20.1 mm Hg at 25 deg C
3.49 (air= 1)
Oral-rat LD50: 460 mg/kg; inhalation-mouse LC50: 3070 mg/m3/2 hours
Inflammable in case of open flame, high temperature, oxidant; burning produces toxic nitrogen oxide fumes
1.8-9.3%(V)
Ammonia odor
5.10e-05 atm-m3/mole|Henry's Law constant = 5.1X10-5 atm-cu m/mole at 25 °C
pKb = 3; pKa = 11 (conjugate acid)
Forms a hydrate with water|Conversion factor: 1 ppm= 4.14 mg/cu m|Amines tends to be fat soluble /Amines/|Liquid heat capacity= 0.600 Btu/lb-F @ 70 °F|For more Other Experimental Properties (Complete) data for DIPROPYLAMINE (8 total), please visit the HSDB record page.
Highly flammable. Soluble in water.
Amines, Phosphines, and Pyridines
DIPROPYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
570 deg F (299 °C)
-18,750 BTU/LB= -10,420 CAL/G= -436.0X10+5 J/KG
44.04 kJ/mol at 25 °C
Critical temperture: 555.8 K; critical pressure: 3.63 MPA
Safety Information
II
3
UN 2383 3/PG 2
1
11-20/21/22-35
16-26-36/37/39-45
JL9200000
F,C
The warehouse is ventilated, low temperature and dry; stored separately from oxidants and acids
Stable. Highly flammable. Incompatible with strong oxidizing agents.
P210-P261-P280-P303 + P361 + P353-P305 + P351 + P338-P370 + P378
H225-H302-H311 + H331-H314
[40 CFR 240-280, 300-306, 702-799 (7/1/2006)] Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U110, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.|Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U110, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.|A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids. A potential candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids. A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds.|/Absorb small spills with paper and/ burn the paper in a suitable location away from combustible materials. Large quantities can be reclaimed or collected & atomized in suitable combustion chamber equipped with appropriate effluent gas cleaning device.
Incompatible with acids, organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks aluminum, copper, lead, tin, zinc, and their alloys.|Can react with oxidizers.
European Chemicals Bureau; IUCLID Dataset, Dipropylamine (142-84-7) (2000 CD-ROM edition). Provides information on usage patterns, ecotoxicity, and toxicity supplied to the European Union by industry.
UN 2383
Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires. (USCG, 1999)|Flammable - 3rd degree
|Danger|H225: Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P363, P370+P378, P403+P235, P405, and P501|H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P310, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P311, P312, P321, P322, P330, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 206 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P311, P312, P321, P322, P330, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P307+P311, P309+P311, P310, P312, P321, P322, P330, P361, P363, P370+P378, P403+P235, P405, and P501
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb with earth, sand or other non-combustible material and transfer to containers (except for Hydrazine). Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)
Self-contained breathing apparatus; butyl rubber gloves; butyl rubber apron; face shield (USCG, 1999)|SRP: When working with strong solutions of acids or bases or other caustic or corrosive materials, always wear a full face mask. When working with caustic or corrosive gases or vapors, a full face mask will not protect the eyes or prevent inhaling the material. A full face respirator is required.|Wear protective gloves and clothing to prevent any reasonable probability of skin contact. Safety equipment suppliers/manufacturers can provide recommendations on the most protective glove/clothing material for your operation. Teflon and Polycarbonate are among the recommended protective materials. Contact lenses should not be worn when working with this chemical. Wear splash-proof chemical goggles and face shield unless full face-piece respiratory protection is worn. Employees should wash immediately with soap when skin is wet or contaminated. Provide emergency showers and eyewash.|SELF-CONTAINED BREATHING APPARATUS; BUTYL RUBBER GLOVES; BUTYL RUBBER APRON; FACE SHIELD.
Forms explosive mixture with air.|A very dangerous fire hazard when exposed to heat or flame.
FOAM; DRY CHEMICAL; CARBON DIOXIDE. ... WATER MAY BE INEFFECTIVE.|If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.
Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Ventilate area of spill or leak. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or a similar material and deposit in sealed containers. Keep this chemical out of confined spaces, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build up of explosive concentrations. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean-up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.|1. REMOVE ALL IGNITION SOURCES; 2. VENTILATE AREA OF SPILL OR LEAK; 3. FOR SMALL QUANTITIES, ABSORB ON PAPER TOWELS. EVAPORATE IN SAFE PLACE (SUCH AS FUME HOOD). ALLOW SUFFICIENT TIME FOR EVAPORATING VAPORS TO COMPLETELY CLEAR THE HOOD DUCTWORK. BURN PAPER IN SUITABLE LOCATION AWAY FROM COMBUSTIBLE MATERIALS.|Environmental considerations-land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents.|Environmental considerations-water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses.|Environmental considerations-air spill: Apply water spray or mist to knock down vapors.
SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.|SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid.|Personnel protection: Avoid breathing vapors. Keep upwind. Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing.
/GUIDE 132: FLAMMABLE LIQUIDS - CORROSIVE/ Fire or Explosion: Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.|/GUIDE 132: FLAMMABLE LIQUIDS - CORROSIVE/ Health: May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.|/GUIDE 132: FLAMMABLE LIQUIDS - CORROSIVE/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 132: FLAMMABLE LIQUIDS - CORROSIVE/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for DIPROPYLAMINE (8 total), please visit the HSDB record page.
Label: "Flammable Liquid, Corrosive." Hazard Class 3. Packing Group II.|No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
CONTACT WITH EYES CAUSES SEVERE IRRITATION ... CONTACT WITH SKIN CAUSES SEVERE IRRITATION.
| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 0 - Materials that in themselves are normally stable, even under fire conditions.
U110; A toxic waste when a discarded commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate.
Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).
U110; As stipulated in 40 CFR 261.33, when dipropylamine, as a commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate, becomes a waste, it must be managed according to Federal and/or State hazardous waste regulations. Also defined as a hazardous waste is any residue, contaminated soil, water, or other debris resulting from the cleanup of a spill, into water or on dry land, of this waste. Generators of small quantities of this waste may qualify for partial exclusion from hazardous waste regulations (40 CFR 261.5).
Dipropylamine was qualitatively identified in soil samples taken from Moscow(1).
Dipropylamine is a constituent of tobacco smoke(1).
Toxicity
highly toxic
Nitrite ... is used as a food additive in meats and smoked fish. Some fish, vegetables, and fruit juices contain secondary amines. The acidic environment of the stomach facilitates a chemical reaction between nitrite and secondary amines, leading to the formation of carcinogenic nitrosamines. /Secondary amines/
LD50 Rat oral 460 mg/kg|LC50 Rat inhalation >8.22 mg/cu m/1 hr|LC50 Rat inhalation 4400 mg/cu m/4 hr|LC50 Mouse inhalation 3070 mg/cu m/2 hr|For more Non-Human Toxicity Values (Complete) data for DIPROPYLAMINE (9 total), please visit the HSDB record page.
... amines from decomposing fish ... /Amines/|Dipropylamine has been found in tobacco(1,2).
Dipropylamine's production and use as a chemical intermediate(1), principally in the production of certain herbicides(2), may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 190(SRC), determined from a log Kow of 1.67(2) and a regression-derived equation(3), indicates that dipropylamine is expected to have moderate mobility in soil(SRC). The pKa of dipropylamine is 11(4) indicating that this compound will exist almost entirely in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of dipropylamine from moist soil surfaces is not expected to be an important fate process given its cationic state(SRC). Dipropylamine is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 20.1 mm Hg(6). Dipropylamine was determined to be biodegradable using the Japanese MITI test protocol(7), suggesting biodegradation may be an important fate process in soil(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 190(SRC), determined from a log Kow of 1.67(2) and a regression-derived equation(3), indicates that dipropylamine is expected to adsorb to suspended solids and sediment(SRC). A pKa of 11(4) indicates dipropylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 4(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Dipropylamine was determined to be biodegradable using the Japanese MITI test protocol(8), suggesting biodegradation may be an important fate process in water(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dipropylamine, which has a vapor pressure of 20.1 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dipropylamine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 4 hours(SRC), from its rate constant of 8.7X10-11 cu cm/molecule-sec at 25 °C that was derived using a structure estimation method(3). Dipropylamine does not contain chromophores that absorb at wavelengths >290 nm(4) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).
The rate constant for the vapor-phase reaction of dipropylamine with photochemically-produced hydroxyl radicals has been estimated as 8.7X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 4 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Dipropylamine is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2). Dipropylamine does not contain chromophores that absorb at wavelengths >290 nm(2) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).
An estimated BCF of 4 was calculated in fish for dipropylamine(SRC), using a log Kow of 1.67(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
The Koc of dipropylamine was estimated as 190(SRC), using a log Kow of 1.67(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that dipropylamine is expected to have moderate mobility in soil(SRC). The pKa of dipropylamine is 11(4) indicating that this compound will exist almost entirely in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
A pKa of 11(1) indicates dipropylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process(2). The potential for volatilization of dipropylamine from dry soil surfaces may exist(SRC) based upon a vapor pressure of 20.1 mm Hg(3).
SURFACE WATER: Dipropylamine was detected at levels ranging from 0.3-3 ppb in various river waters from W Germany(1).
The following concns (in mg/kg) of dipropylamine were detected in various food products from W Germany: preserved broken beans, 1.0; preserved shelled peas, 0.1; preserved red cabbage, 0.1; paprika, 0.3; paprika brine, 2.0; cucumber, 0.1-1.4; pickled onions, 1.1; celery, 0.9; cheese, 8.4; brown bread, 0.4(1). Trace levels (<0.1 ppm) were detected in baked ham(2). Dipropylamine was identified, not quantified, in boiled beef(3). Dipropylamine was detected in baked ham at a concn of 0.007 ppm(4).
Occupational exposure to dipropylamine may occur through inhalation and dermal contact with this compound at workplaces where dipropylamine is produced or used. Monitoring data indicate that the general population may be exposed to dipropylamine via ingestion of food and the use of tobacco products products containing dipropylamine. (SRC)
| Name | Type of Test | Exposure Route | Species Observed | Dose/Duration | Toxic Effects | Reference |
|---|---|---|---|---|---|---|
| SKIN/EYE IRRITATION DATA | Open irritation test | Administration onto the skin | Rodent - rabbit | 100 ug/24H | -- | American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 |
| SKIN/EYE IRRITATION DATA | LD50 - Lethal dose, 50 percent kill | Oral | Rodent - rat | 460 mg/kg | Details of toxic effects not reported other than lethal dose value-- | Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,63,1982 |
| SKIN/EYE IRRITATION DATA | LC50 - Lethal concentration, 50 percent kill | Inhalation | Rodent - rat | 4400 mg/m3/4H | Details of toxic effects not reported other than lethal dose value-- | Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,63,1982 |
Drug Information
Dipropylimine is a known human metabolite of NDPA.
When administered ip to rats, dipropylamine was a moderate inhibitor of liver monoamine oxidase activity. Possible relations between effects of alkylamines on MAO activity and changes in serotonin metabolism discussed.
Inhalation causes severe coughing and chest pain due to irritation of air passages; can-cause lung edema; may also cause headache, nausea, faintness, and anxiety. Ingestion causes irritation and burning of mouth and stomach. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation. (USCG, 1999)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Organic bases/Amines and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. If patient is unresponsive to these measures, vasopressors may be helpful. Watch for signs of fluid overload ... . Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Organic bases/Amines and related compounds/
/SIGNS AND SYMPTOMS/ Inhalation causes severe coughing and chest pain due to irritation of air passages; can cause lung edema; may also cause headache, nausea, faintness, and anxiety. Ingestion causes irritation and burning of mouth and stomach. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation.|/OTHER TOXICITY INFORMATION/ Moderately toxic by skin contact and inhalation.|/OTHER TOXICITY INFORMATION/ Since the amines are bases and may form strongly alkaline solutions, they can be damaging if splashed in the eye or if allowed to contaminate the skin. Otherwise they have no specific toxic properties, and the lower aliphatic amines are normal constituents of body tissues, so that they occur in a large number of foods, particularly fish, to which they impart a characteristic odor. One area of concern at present is the possibility that some aliphatic amines may react with nitrate or nitrite in vivo to form nitroso compounds, many of which are known to be potent carcinogens in animals ... . /Aliphatic amines/
Dipropylamine Use and Manufacturing
The preparation method is obtained by using propanol as a raw material through catalytic dehydrogenation, amination, dehydration and hydrogenation. The reaction catalyst is Ni-Cu-Al2O3, the pressure is (39±1)kPa, the reactor temperature is (190±10)℃, the space velocity of propanol is 0.05~0.15h-1, the ratio of raw materials is propanol: ammonia :Hydrogen=4:2:4, dipropylamine and tripropylamine can be obtained at the same time, and dipropylamine can be obtained by fractional distillation.
Solvents and intermediates used in the production of medicines, pesticides, dyes, mineral flotation agents, emulsifiers and fine chemicals. Used in the preparation of pesticides; medicines (dipropyl glutamine, etc.); boiler preservatives; engine coolants; lubricating oils; metal cutting oils; carbon removal agents; corrosion-resistant lubricants, emulsifiers, and solvents. Among them, pesticide is the most important use. The main pesticides produced by dipropylamine: trifluralin; difluralin; diflubenzuron; carbendazim; disulfiram; disulfiram; isoprofloxacin; difluralin; diflubenzuron; propofol.
Adhesives and sealant chemicals
Adhesives and sealants
10,000,000 - 50,000,000 lb|(1972) 7.6X10+9 GRAMS|(1974) 1.11X10+10 GRAMS|(1981) 26,439X10+3 lb|(1984) 1.86X10+10 g|For more U.S. Production (Complete) data for DIPROPYLAMINE (6 total), please visit the HSDB record page.
97% min|Grades or purity: Technical, 98%; pure, 99+%|Technical
Adhesive manufacturing|1-Propanamine, N-propyl-: ACTIVE
A MIXT OF 13 LOWER ALIPHATIC AMINES WERE SEPARATED IN A TENAX-GC COLUMN BY TEMP PROGRAMMING GAS CHROMATOGRAPHY. /ALIPHATIC AMINES/|ORG CONTAMINANTS, INCL DIPROPYLAMINE, IN CINCINNATI (OHIO), USA, DRINKING WATER WERE CONCENTRATED BY REVERSE OSMOSIS/LYOPHILIZATION METHOD & IDENTIFIED BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY.|THE COMPOSITION OF N-CONTAINING ORG BASES IN THE VOLATILE SUBSTANCES OF BOILED BEEF WAS STUDIED. 30 CMPD WERE IDENTIFIED INCL PRIMARY, SECONDARY & TERTIARY ALIPHATIC AMINES. /AMINES/|METHODS ARE GIVEN FOR THE SEPARATION & DETERMINATION OF AMINO ACIDS, DIPEPTIDES & AMINES BY ION-PAIR HPLC USING SODIUM NAPHTHALENE-2-SULFONATE AS COUNTER ION IN THE AQ STATIONARY PHASE. DOWN TO 0.1 NANOMOLES (ABOUT 10 NG) CAN BE QUANTIFIED WITH FAIRLY GOOD PRECISION BY PEAK AREA MEASUREMENT USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. /AMINES/|For more Analytic Laboratory Methods (Complete) data for DIPROPYLAMINE (6 total), please visit the HSDB record page.
Fire Hazards -> Flammable - 3rd degree
Computed Properties
Molecular Weight:101.19
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:101.120449483
Monoisotopic Mass:101.120449483
Topological Polar Surface Area:12
Heavy Atom Count:7
Complexity:23.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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