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Bucetin

Bucetin structure

CAS No:
1083-57-4
Formula:
C12H17NO3
Chemical Name:
Bucetin
Synonyms:
Butanamide,N-(4-ethoxyphenyl)-3-hydroxy-;p-Butyrophenetidide,3-hydroxy-;N-(4-Ethoxyphenyl)-3-hydroxybutanamide;Bucetin;3-Hydroxy-p-butyrophenetidide;β-Hydroxybutyric acid p-phenetidide;p-Ethoxy-N-(β-hydroxybutyryl)aniline;Betadid;N-(β-Hydroxybutyryl)-p-phenetidine;(±)-Bucetin;156674-12-3
Categories:
Analytical Chemistry > Standard

Description

Bucetin (3-Hydroxy-p-butyrophenetidide) is an analgesic and antipyretic compound.

Bucetin is an organic molecular entity.|Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.

Bucetin Basic Attributes

Molecular Weight：

223.27

Exact Mass：

223.27

EC Number：

214-109-8

UNII：

1Z23WB033I|PLF54F8S2F

NSC Number：

759243|320045

DSSTox ID：

DTXSID6020721

ATC Code：

N - Nervous system

HScode：

2924299090

Characteristics

PSA：

58.6

XLogP3：

1.8

Density：

1.1223 (rough estimate)

Melting Point：

160 °C

Boiling Point：

364.56°C (rough estimate)

Flash Point：

216ºC

Refractive Index：

1.5300 (estimate)

Vapor Pressure：

2.77E-08mmHg at 25°C

Toxicity：

LD50 in mice (mg/kg): 790 i.p., 2800 orally (Fujimura)

Collision Cross Section：

152.5 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Packing level：

Ⅲ

Transport codes：

2811

wgk germany：

hazard class code：

45-46-20/21/22

safety instructions：

53-22-36/37/39-45

RTECS Number：

EU0900000

Marks：

Precautionary statement(s)：

P201-P280-P308 + P313

Hazard Statements：

H312-H332-H350

GHS Classification：

|Danger|H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]|P201, P202, P261, P271, P280, P281, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P363, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

beta-hydroxybutyric acid-p-phenetidide

Bucetin Use and Manufacturing

Uses

Bucetin is an antipyretic and analgesic drug that is chemically similar to phenacetin (P294580). The use of Bucetin has been withdrawn due to renal toxicity.

Manufacturing Info：

Butanamide, N-(4-ethoxyphenyl)-3-hydroxy-: INACTIVE

Use Classification：

Pharmaceuticals

Computed Properties

Molecular Weight:223.27
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:223.12084340
Monoisotopic Mass:223.12084340
Topological Polar Surface Area:58.6
Heavy Atom Count:16
Complexity:212
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Bucetin

Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

3-HYDROXY-P-BUTYROPHENETIDINE 99% see COA Kanbei kanbei

CAS No.: 1083-57-4

Grade: Industrial Grade

Content: 99%

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