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Arresten

Arresten structure

CAS No:
1084-65-7
Formula:
C10H13NO4S2
Chemical Name:
Arresten
Synonyms:
2H-1-Benzothiopyran-7-sulfonamide,3,4-dihydro-6-methyl-,1,1-dioxide;Thiochroman-7-sulfonamide,6-methyl-,1,1-dioxide;6-Methyl-7-sulfamide-thiochromane 1,1-dioxode;Meticrane;Meticran;6-Methylthiochroman-7-sulfonamide 1,1-dioxide;6-Methyl-7-sulfamoylthiochroman 1,1-dioxide;Fontilix;E 103E;SD 171-02;Arresten;SD 17102
Categories:
Analytical Chemistry > Standard

Description

Meticrane is a diuretic. Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.

Meticrane is a thiochromane.|Meticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure.|Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity. Meticrane acts in a similar manner as the thiazide diuretics.

Arresten Basic Attributes

Molecular Weight：

275.34

Exact Mass：

275.34

EC Number：

214-112-4

UNII：

I7EKN1924Q

NSC Number：

759309

DSSTox ID：

DTXSID9045346

NCI Thesaurus Code：

C66125

ATC Code：

C - Cardiovascular system

HScode：

2935009090

Characteristics

PSA：

111

XLogP3：

0.5

Density：

1.4366 (rough estimate)

Melting Point：

236.5 °C

Boiling Point：

549.1±60.0 °C(Predicted)

Flash Point：

285.9ºC

Refractive Index：

1.6800 (estimate)

Storage Conditions：

-20°C

Collision Cross Section：

159.4 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

XK6360000

Arresten Use and Manufacturing

diuretic, antihypertensive

Computed Properties

Molecular Weight:275.3
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:275.02860024
Monoisotopic Mass:275.02860024
Topological Polar Surface Area:111
Heavy Atom Count:17
Complexity:485
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes