Cefodizime sodiumCAS:86329-79-5Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Cefodizime sodiumCAS:86329-79-5Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS No:
86329-79-5
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Formula:
C20H20N6O7S4.2Na
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Chemical Name:
Cefodizime sodiumCAS:86329-79-5Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,sodium salt (1:2),(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt,[6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-,disodium salt,(6R,7R)-;THR 221;Cefodizime sodium;Cefodizime disodium;HR 221;S 77-1221B;Cefodizime disodium salt;Timecef;Kenicef
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CAS No:
Description
Cefodizime sodium is a third generation cephalosporin with a broad spectrum of antibacterial activity[1]. Cefodizime sodium has some peculiar merits such as no renal toxic effect, good tolerance and even the activity of immune regulation，and is widely used in the treatment of severe infections of the respiratory and urinary tracts[2].
Cefodizime sodiumCAS:86329-79-5Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg Basic Attributes
628.63
627.991516
617-833-6
DTXSID9046730
Characteristics
310
-0.76070
White to yellow crystalline powder
LD50 in mice, rabbits (mg/kg): 4000-8000 i.v. both species; in rats (mg/kg): 4000-8000 i.v., 15000-17500 s.c., 8000-11000 i.p. (Bryskier)
Safety Information
|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 3 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Computed Properties
Molecular Weight:628.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:627.99152019
Monoisotopic Mass:627.99152019
Topological Polar Surface Area:310
Heavy Atom Count:39
Complexity:1020
Defined Atom Stereocenter Count:2
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
This product belongs to the third generation of cephalosporin, has a broad-spectrum antibacterial effect, and is stable to β-lactamase produced by most bacteria. This product is mainly effective against a variety of G and G- bacteria and anaerobic bacteria. It has an immunomodulatory effect, that is, it can be used as a biological response modifier (BRM) to increase CD4 in the body, thereby increasing the CD4/CD8 value and playing a synergistic bactericidal effect. The mechanism of action of this product is that this product achieves a bactericidal effect by inhibiting the biosynthesis of bacterial cell wall mucopeptides.
Registered Holders
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Amicogen(China) Biopharm Co., Ltd.
Active
China
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CSPC Zhongnuo PHARMACEUTICAL(Shijiazhuang) Co., Ltd.
Active
China
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Zhejiang Yongning Pharmaceutical Co., Ltd.
Active
China
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Cefodizime sodiumCAS:86329-79-5Purity:98% (Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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