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Home > Active Pharmaceutical Ingredients > Digestive System Drugs (Find 15 items)

Sodium bicarbonate

(144-55-8)
Used in food, medicine, film production, tanning, beneficiation, metallurgy, fiber, rubber and other industries. It can also be used as a detergent and fire extinguishing agent as a fermentation agent in the food industry. Carbon dioxide generators in carbonated water and cold drinks are used for analysis Reagents, also used in inorganic synthesis and pharmaceutical industry for the treatment of acidemia used as a fermenting agent for the food industry, a carbon dioxide generator in soft drinks

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Sodium sulfate

(7757-82-6)
It can be mainly used as the filler of synthetic detergent. Paper industry applies it for the cooking agent during the manufacture of sulfate pulp. Glass industry uses it as substitute of soda. Chemical industry applies it as the raw material for the manufacturing of sodium sulfide, sodium silicate and other chemical products. Textile industry applies it for the formulation of Vinylon spinning coagulation bath. The pharmaceutical industry applies it as laxatives. It can also be used in non-ferro

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Sofosbuvir

(1190307-88-0)
PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.[Cayman Chemical]

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Sucralfate

(54182-58-0)
An inhibitor of peptic hydrolysis and stomach acidity.Used as an antiulcerative

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Sodium bis(2-ethylhexyl) sulfosuccinate

(577-11-7)
Wetting agent in industrial, pharmaceutical, cosmetic & food applications, dispersing and solubilizing agent in foods, adjuvant in tablet formation.This product is an excellent emulsifier, detergent and penetrant used in the textile industry. Good permeability and wettability. Thickener; emulsifier; wetting agent. Surfactant, emulsifier, wetting agent. Also called aerosol OT, it is used as a lubricant, and can be used as a surfactant in the printing and dyeing industry and the cosmetics industry

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Simethicone

(8050-81-5)
Simethicone is an oral anti-foaming agent used to reduce bloating, discomfort and pain caused by excess gas in the stomach or intestinal tract. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel.

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Swertiamarin

(17388-39-5)
It has the functions of protecting liver and stomach.

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Sodium taurocholate

(145-42-6)
selectively activates retinoid X receptors (RXRs)

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Sofalcone

(64506-49-6)
Sofalcone is an anti-ulcer chalcone derivative. It blocks inflammation by suppressing the production of nitric oxide, TNF-α, and MCP-1 while inducing the expression of heme oxygenase-1 when used at 10-20 μM. Sofalcone (20-50 μM) induces VEGF expression in gastric epithelial cells and promotes gastric ulcer healing following eradication therapy for H. pylori.[Cayman Chemical]

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Digestive system drugs are currently one of the most commonly used drugs in clinic. Digestive System Drugs mainly include liver disease drugs, antacid and mucosal protective drugs, cholagogue drugs, appetite suppressants and other diet pills, gastrointestinal motility drugs, gastrointestinal antispasmodic drugs, laxatives and antidiarrheal Medicines, gastric acid Inhibitors, emetics and antiemetics, digestant drugs and other digestive system drugs. The "Digestive System Drugs" of ECHEMI classification list mainly supplies APIs for such drugs.

Frequently Asked Questions

What are Digestive System Drugs used for?

Digestive System Drugs are medications designed to treat a wide range of gastrointestinal (GI) disorders, including acid reflux, peptic ulcers, irritable bowel syndrome (IBS), constipation, diarrhea, and inflammatory bowel disease (IBD). These drugs work by regulating digestive processes, reducing inflammation, neutralizing stomach acid, or modulating gut motility. They play a critical role in improving patients’ quality of life and managing chronic GI conditions effectively.

What are the common types of Digestive System Drugs?

Common types of Digestive System Drugs include:1. Antacids and H2 receptor antagonists (e.g., ranitidine) for reducing stomach acid.2. Proton pump inhibitors (PPIs) like omeprazole for long-term acid suppression.3. Laxatives and antidiarrheals for bowel regulation.4. Prokinetic agents that enhance gastrointestinal motility.5. Anti-inflammatory drugs such as mesalamine for IBD.Each class targets specific symptoms or underlying mechanisms of digestive diseases.

How do I choose a reliable supplier for Digestive System Drugs?

When selecting a supplier for Digestive System Drugs, consider the following criteria:1. Regulatory compliance—ensure the supplier holds valid GMP, FDA, or EMA certifications.2. Quality assurance—look for documented quality control procedures and batch testing.3. Product portfolio breadth—including APIs, finished formulations, and intermediates.4. Supply chain reliability and global distribution capabilities.5. Technical support and regulatory documentation assistance.Partnering with a reputable supplier minimizes risk and ensures consistent product quality.

Are there safety concerns with long-term use of Digestive System Drugs?

Yes, prolonged use of certain Digestive System Drugs may carry risks. For example, long-term proton pump inhibitor (PPI) use has been associated with vitamin B12 deficiency, increased fracture risk, and kidney issues. Chronic laxative use can lead to electrolyte imbalances and dependency. It’s essential to use these medications under medical supervision, adhere to prescribed dosages, and periodically reassess treatment necessity to mitigate potential adverse effects.

What are the latest trends in Digestive System Drug development?

Recent trends in Digestive System Drug development include:1. Targeted biologics and small molecules for IBD, such as JAK inhibitors and anti-TNF agents.2. Microbiome-based therapies aiming to restore gut flora balance.3. Personalized medicine approaches using genetic and biomarker profiling.4. Improved drug delivery systems (e.g., pH-sensitive coatings) for site-specific action in the GI tract.These innovations reflect a shift toward more effective, safer, and patient-tailored treatments for complex digestive disorders.

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