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Home > Active Pharmaceutical Ingredients > Digestive System Drugs (Find 15 items)

Tetrahydrolipstatin

(96829-58-2)
1. An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent.
2. Antidiabetic
3. Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor.
4. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrol

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Tiopronin

(1953-02-2)
It is used as antidote against heavy metal poisoning; hepatoprotectant; mucolytic. It can activate metabolic enzymes, and can chelate with toxic substances that hinder HS-enzyme activity, so it has a detoxification effect. It is mainly used for the treatment of acute and chronic hepatitis, liver cirrhosis, alcoholic liver damage and liver damage caused by drugs. It can also be used for metal poisoning, chemotherapy and radiotherapy protection, urticaria, dermatitis, eczema and acne. It is mainl

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Tizanidine

(51322-75-9)
Labeled Tizanidine, intended for use as an internal standard for the quantification of Tizanidine by GC- or LC-mass spectrometry.

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Tizanidine hydrochloride

(64461-82-1)
An α2-adrenergic agonist; centrally active myotonolytic. A muscle relaxant (skeletal).

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Teprenone

(6809-52-5)
An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces ex

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trans-3,7-Dimethyl-2,6-octadienyl 5,9,13-trimethyl-4,8,12-tetradecatrienoate

(51-77-4)
Gefarnate is a drug used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome.

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Thiethylperazine

(1420-55-9)
ChEBI: A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2.

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Troxipide

(30751-05-4)
Troxipide is a drug used in the treatment of gastroesophageal reflux disease. Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. Troxipide is currently marketed in Japan (Aplace), China (Shuqi), South Korea (Defensa), and India (Troxip). It is used for the management of gastric ulcers, and amelioration of gastric mucosal lesions in acute gastritis and acute exace

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Digestive system drugs are currently one of the most commonly used drugs in clinic. Digestive System Drugs mainly include liver disease drugs, antacid and mucosal protective drugs, cholagogue drugs, appetite suppressants and other diet pills, gastrointestinal motility drugs, gastrointestinal antispasmodic drugs, laxatives and antidiarrheal Medicines, gastric acid Inhibitors, emetics and antiemetics, digestant drugs and other digestive system drugs. The "Digestive System Drugs" of ECHEMI classification list mainly supplies APIs for such drugs.

Frequently Asked Questions

What are Digestive System Drugs used for?

Digestive System Drugs are medications designed to treat a wide range of gastrointestinal (GI) disorders, including acid reflux, peptic ulcers, irritable bowel syndrome (IBS), constipation, diarrhea, and inflammatory bowel disease (IBD). These drugs work by regulating digestive processes, reducing inflammation, neutralizing stomach acid, or modulating gut motility. They play a critical role in improving patients’ quality of life and managing chronic GI conditions effectively.

What are the common types of Digestive System Drugs?

Common types of Digestive System Drugs include:1. Antacids and H2 receptor antagonists (e.g., ranitidine) for reducing stomach acid.2. Proton pump inhibitors (PPIs) like omeprazole for long-term acid suppression.3. Laxatives and antidiarrheals for bowel regulation.4. Prokinetic agents that enhance gastrointestinal motility.5. Anti-inflammatory drugs such as mesalamine for IBD.Each class targets specific symptoms or underlying mechanisms of digestive diseases.

How do I choose a reliable supplier for Digestive System Drugs?

When selecting a supplier for Digestive System Drugs, consider the following criteria:1. Regulatory compliance—ensure the supplier holds valid GMP, FDA, or EMA certifications.2. Quality assurance—look for documented quality control procedures and batch testing.3. Product portfolio breadth—including APIs, finished formulations, and intermediates.4. Supply chain reliability and global distribution capabilities.5. Technical support and regulatory documentation assistance.Partnering with a reputable supplier minimizes risk and ensures consistent product quality.

Are there safety concerns with long-term use of Digestive System Drugs?

Yes, prolonged use of certain Digestive System Drugs may carry risks. For example, long-term proton pump inhibitor (PPI) use has been associated with vitamin B12 deficiency, increased fracture risk, and kidney issues. Chronic laxative use can lead to electrolyte imbalances and dependency. It’s essential to use these medications under medical supervision, adhere to prescribed dosages, and periodically reassess treatment necessity to mitigate potential adverse effects.

What are the latest trends in Digestive System Drug development?

Recent trends in Digestive System Drug development include:1. Targeted biologics and small molecules for IBD, such as JAK inhibitors and anti-TNF agents.2. Microbiome-based therapies aiming to restore gut flora balance.3. Personalized medicine approaches using genetic and biomarker profiling.4. Improved drug delivery systems (e.g., pH-sensitive coatings) for site-specific action in the GI tract.These innovations reflect a shift toward more effective, safer, and patient-tailored treatments for complex digestive disorders.

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