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Flavonoids

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5-Hydroxy-7,4′-dimethoxyflavone

(5128-44-9)
The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines.And it also showed inhibition of the drug efflux pumps (with IC50 = 51.64 μg/ml).IC50:51.64 μg/ml(Candida albicans drug efflux pumps)[2]In vitro: The isolated 7,4'-Di-O-methylapigenin was further investigated for its inhibitory activity on ABC drug efflux pumps in C. alb

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5-hydroxy-7,8-dimethoxyflavone

(3570-62-5)
Moslosooflavone is a flavonoid isolated from Saussurea involucrata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities[1].

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5,4′-Dihydroxyflavone

(6665-67-4)
4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.

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Flavonoids, also known as bioflavonoids (bioflavonoids), are a type of compound that exists in nature and has a 2-phenyl flavonone structure. Widely distributed in the plant kingdom, it is a large class of important natural compounds. Flavonoids mostly have colors, and their different colors add more colors to the family of natural pigments.

Frequently Asked Questions

What are flavonoids and why are they important?

Flavonoids are a diverse group of phytonutrients found in almost all fruits and vegetables. They are known for their antioxidant, anti-inflammatory, and immune-supporting properties. Common subclasses include flavones, flavonols, flavanones, isoflavones, and anthocyanidins. Due to their health-promoting effects, flavonoids are widely used in dietary supplements, functional foods, and natural therapeutics.

What are the common natural sources of flavonoids?

Flavonoids occur naturally in a wide variety of plant-based foods and beverages. Rich sources include citrus fruits (flavanones), berries (anthocyanidins), onions and apples (flavonols), soybeans (isoflavones), and tea—especially green and black tea (catechins and theaflavins). Including a colorful diet with diverse fruits, vegetables, legumes, and herbs helps ensure adequate flavonoid intake.

What should buyers consider when sourcing high-quality flavonoid extracts?

When sourcing flavonoid extracts, buyers should evaluate:1. Purity and concentration levels (e.g., HPLC-certified assays).2. Botanical origin and extraction method (e.g., solvent-free or ethanol-based).3. Compliance with regulatory standards like ISO, GMP, or FDA GRAS status.4. Supplier transparency regarding heavy metals, pesticides, and microbial testing.5. Batch-to-batch consistency and documentation (Certificates of Analysis).These factors ensure safety, efficacy, and suitability for end-use applications.

Are there different types of flavonoid compounds used commercially?

Yes, several flavonoid compounds are commonly used in commercial products. Key examples include quercetin (a flavonol with strong antioxidant activity), hesperidin (a citrus flavanone supporting vascular health), epigallocatechin gallate (EGCG from green tea, known for metabolism support), genistein (a soy isoflavone used in hormonal health formulations), and rutin (used for capillary strength and anti-edema effects). Each type offers distinct biological activities and application benefits.

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