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Home > Natural Products > Flavonoids (Find 28 items)

Flavonoids

Acacetin

(480-44-4)
VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood.

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Amentoflavone

(1617-53-4)
Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects.IC50 value:Target:In vitro: In irradiated v79 cells, Pretreatment with amentoflavone 24 hours prior to 8 Gy 60Co γ-ray irradiation significantly inhibited apoptosis, promoted the G2 phase, decreased the concentration of ROS and mitochondrial mass [2]. Amentoflavone dose-dependently inhibited the viability of SW480 cells, and a high concent

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Astilbin

(29838-67-3)
Astilbin, a flavonoid compound, is isolated from the rhizome of Smilax glabra. Astilbin enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation.

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Avicularin

(572-30-5)
Avicularin is a bio-active flavonoid from plants, anti-inflammatory, anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF κB (p65), COX 2 and PPAR γ activities[1][2].

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Artemetin

(479-90-3)
Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity[1].

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Afzelin

(482-39-3)
Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found in Houttuynia cordata Thunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1. Afzelin improves the survival rate and reduces the serum levels of alanine aminotrans

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Afzelechin

(2545-00-8)
ChEBI: A tetrahydroxyflavan that is (2S)-flavan substituted by hydroxy groups at positions 3, 5, 7 and 4' respectively.

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Flavonoids, also known as bioflavonoids (bioflavonoids), are a type of compound that exists in nature and has a 2-phenyl flavonone structure. Widely distributed in the plant kingdom, it is a large class of important natural compounds. Flavonoids mostly have colors, and their different colors add more colors to the family of natural pigments.

Frequently Asked Questions

What are flavonoids and why are they important?

Flavonoids are a diverse group of phytonutrients found in almost all fruits and vegetables. They are known for their antioxidant, anti-inflammatory, and immune-supporting properties. Common subclasses include flavones, flavonols, flavanones, isoflavones, and anthocyanidins. Due to their health-promoting effects, flavonoids are widely used in dietary supplements, functional foods, and natural therapeutics.

What are the common natural sources of flavonoids?

Flavonoids occur naturally in a wide variety of plant-based foods and beverages. Rich sources include citrus fruits (flavanones), berries (anthocyanidins), onions and apples (flavonols), soybeans (isoflavones), and tea—especially green and black tea (catechins and theaflavins). Including a colorful diet with diverse fruits, vegetables, legumes, and herbs helps ensure adequate flavonoid intake.

What should buyers consider when sourcing high-quality flavonoid extracts?

When sourcing flavonoid extracts, buyers should evaluate:1. Purity and concentration levels (e.g., HPLC-certified assays).2. Botanical origin and extraction method (e.g., solvent-free or ethanol-based).3. Compliance with regulatory standards like ISO, GMP, or FDA GRAS status.4. Supplier transparency regarding heavy metals, pesticides, and microbial testing.5. Batch-to-batch consistency and documentation (Certificates of Analysis).These factors ensure safety, efficacy, and suitability for end-use applications.

Are there different types of flavonoid compounds used commercially?

Yes, several flavonoid compounds are commonly used in commercial products. Key examples include quercetin (a flavonol with strong antioxidant activity), hesperidin (a citrus flavanone supporting vascular health), epigallocatechin gallate (EGCG from green tea, known for metabolism support), genistein (a soy isoflavone used in hormonal health formulations), and rutin (used for capillary strength and anti-edema effects). Each type offers distinct biological activities and application benefits.

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