AbbVie’s $2.5B Drug Venetoclax Fails to Improve Survival in Phase 3 Trial
On June 17, 2025, AbbVie announced that its blockbuster cancer drug venetoclax failed to meet the primary endpoint of overall survival (OS) in patients with higher-risk myelodysplastic syndrome (HR-MDS) during the VERONA Phase 3 trial. The hazard ratio (HR) was reported at 0.908, indicating no significant benefit.
The global trial compared venetoclax combined with azacitidine to azacitidine plus placebo. Despite the disappointing results, the company confirmed the outcome will not affect the drug's existing approvals. Venetoclax, co-developed with Roche, is currently used to treat chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML).
In 2024, venetoclax generated $2.5 billion in global sales. AbbVie stated that further data from the trial will be presented at an upcoming medical congress. The drug, marketed as Venclexta in the US, is known for targeting the BCL-2 protein, which prevents cancer cell death, helping restore apoptosis.
You May Interested In
SS-31 Cosmetic peptides, discounted price improving cognitive impairment factory supply
$8E+1/UNIT FOB
2026-09-10
Trade Alert
Delivering the latest product trends and industry news straight to your inbox.
(We'll never share your email address with a third-party.)
Related News
-
Evonik and AMSilk Expand Collaboration to Develop Sustainable Biotech Silk Materials
-
BASF and Clariant Exit Quietly! Behind Henkel’s High-Priced Acquisition, Why Did Former Allies Choose to “Let Go”?
-
INEOS Inovyn Moths Methyl Chlorocarbonate Production Facility in Tavaux, France
-
Beiersdorf Launches Eucerin Skincare Brand in Japan
-
Henkel's Acquisition of Stahl Enters Regulatory Countdown: Will the €2.1 Billion Deal Go Through?
-
The Pill That Could Swallow the Needle: Novo Nordisk Launches Oral Wegovy in U.S. Weight-Loss Revolution
-
From Desert Sands to Dining Tables: Arab Food & Beverage Sector Emerges as Investment Powerhouse
-
Korea’s Petrochemical Pivot: Industry Embraces Historic Restructuring to Slash Overcapacity
-
Dafeng Haijianuo’s RMB 246 Million Technical Revamp Project Takes Shape, with Multiple Production Lines for Vitamin K1, Folic Acid, and Others Under Construction
-
LANXESS Expands Rubber Additives Production at Qingdao Plant
Recommend Reading
-
![Brenntag Expands Distribution of Givaudan’s Active Beauty Ingredients to Malaysia and Singapore]()
Brenntag Expands Distribution of Givaudan’s Active Beauty Ingredients to Malaysia and Singapore
-
![BASF’s Price Increase Shows Pharma Excipients Are Still Exposed to Chemical Cost Pressure]()
BASF’s Price Increase Shows Pharma Excipients Are Still Exposed to Chemical Cost Pressure
-
![After Two Price Hikes in One Week, Dow Has Fully Exposed the Most Sensitive Nerve in Europe’s Polyurethane Market]()
After Two Price Hikes in One Week, Dow Has Fully Exposed the Most Sensitive Nerve in Europe’s Polyurethane Market
-
![Syngenta’s VIRESTINA Targets Resistant Weeds as Herbicide Innovation Regains Urgency]()
Syngenta’s VIRESTINA Targets Resistant Weeds as Herbicide Innovation Regains Urgency
-
![Cyclohexane Explained: Properties, Uses & Differences from Cyclohexene]()
Cyclohexane Explained: Properties, Uses & Differences from Cyclohexene
-
![Butadiene rubber prices fall back to pre-Middle East conflict levels in China]()
Butadiene rubber prices fall back to pre-Middle East conflict levels in China
-
![Optimistic Expectations for US-Iran Talks Lead to Sharp Drop in Oil Prices, Long-term Supply and Demand Dynamics Remain Uncertain]()
Optimistic Expectations for US-Iran Talks Lead to Sharp Drop in Oil Prices, Long-term Supply and Demand Dynamics Remain Uncertain
-
![Business Society’s September 7, 2026 Styrene Market Outlook: Volatile Trend]()
Business Society’s September 7, 2026 Styrene Market Outlook: Volatile Trend
-
![Business Society’s MTBE Market Outlook on August 20, 2026: Clearly Upward Trend]()
Business Society’s MTBE Market Outlook on August 20, 2026: Clearly Upward Trend
-
![Winter Storms Combined with Geopolitical Tensions Drive Oil Prices Up 3% in a Single Day]()
Winter Storms Combined with Geopolitical Tensions Drive Oil Prices Up 3% in a Single Day
